Results 91 to 100 of about 28,399 (260)

Mānuka Honey and Leaf Bioactives: A Review of Taonga Natural Products From Leptospermum scoparium

New Zealand Journal of Botany, Volume 64, Issue 4, December 2026.
This comprehensive review of mānuka examines its cultural significance, botany, distinct genetics and unique phytochemistry. It highlights mānuka honey, enriched with antibacterial methylglyoxal derived from nectar dihydroxyacetone, and details markers used to combat honey fraud.
John W. van Klink, Suzanne M. Scheele, Nigel B. Perry   +2 more
wiley   +1 more source

Methylglyoxal Binding to Bovine Liver Catalase Results in Loss of Activity and Heme Dislocation

Trends in Peptide and Protein Sciences, 2019
Glycation, the non-enzymatic attachment of glucose to protein, is one of the important events in the pathophysiology of diabetes mellitus, Alzheimer’s, Parkinson’s and other diseases.
Subramanian Sivakami, Sejal A Shah, George Suji, Vikrant M Bhor, Ahmad Ali   +4 more
doaj   +1 more source

Phenylpyrrole fungicides act on triosephosphate isomerase to induce methylglyoxal stress and alter hybrid histidine kinase activity

Scientific Reports, 2019
Fludioxonil, a natural product of pyrrolnitrin, is a potent fungicide used on crops worldwide. Drug action requires the presence of a group III hybrid histidine kinase (HHK) and the high osmolarity glycerol (HOG) pathway.
T. Tristan Brandhorst, I. Kean, Stephanie M. Lawry, Darin L. Wiesner, B. Klein   +4 more
semanticscholar   +1 more source

Important but Overlooked Reactive Organic Carbon (ROC) Air Pollution From Permafrost Wildfires in Canada

Geophysical Research Letters, Volume 53, Issue 21, 16 November 2026.
Abstract Canadian permafrost wildfires, characterized by surface flaming and deep organic soil smoldering, emit complex suites of volatile organic compounds (VOCs). These emissions include air toxics that pose substantial public health risks and fuel secondary pollution, yet remain understudied.
Xueying Liu, Zejiang Yu, Yifang Ban, Hemraj Bhattarai, Theodore K. Koenig, Lingcao Huang, Enze Zhang, Claire Granier, Guy Brasseur, Zhe Wang, Jimmy C. H. Fung   +10 more
wiley   +1 more source

Assay of methylglyoxal and glyoxal and control of peroxidase interference

, 2014
Methylglyoxal and glyoxal are endogenous α-oxoaldehyde metabolites and substrates of the glyoxalase system. These and related α-oxoaldehydes are often determined in cell, tissue and body fluid samples by derivatization with 1,2-diaminobenzene and similar
Rabbani, Naila, Thornalley, Paul J.
core   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source

Effect of protein glycation by methylglyoxal on pancreatic beta cell function [PDF]

Methylglyoxal is a physiological dicarbonyl metabolite and potent argininedirected glycating agent. It often modifies proteins at functional sites producing loss of positive charge, structural distortion and inactivation.
Tym, Amy
core  

Optimizing enzyme properties to enhance dihydroxyacetone production via methylglyoxal biosensor development

Microbial Cell Factories
Background Dihydroxyacetone (DHA) stands as a crucial chemical material extensively utilized in the cosmetics industry. DHA production through the dephosphorylation of dihydroxyacetone phosphate, an intermediate product of the glycolysis pathway in ...
Kaibo Zhang, Mengying Li, Jinsheng Wang, Guozhong Huang, Kang Ma, Jiani Peng, Haoyue Lin, Chunjie Zhang, Honglei Wang, Tao Zhan, Zhe Sun, Xueli Zhang   +11 more
doaj   +1 more source

Boron Reduced Copper Excess-Induced Oxidative Damage in Citrus sinensis by Modulating Reactive Oxygen Species and Methylglyoxal Formation and Their Detoxification Systems

Antioxidants
Citrus is mainly cultivated in acid soil with low boron (B) and high copper (Cu). In this study, Citrus sinensis seedlings were submitted to 0.5 (control) or 350 μM Cu (Cu excess or Cu exposure) and 2.5, 10, or 25 μM B for 24 weeks.
Xu-Feng Chen, Huan-Huan Chen, Wei-Lin Huang, Wei-Tao Huang, Zeng-Rong Huang, Lin-Tong Yang, Xin Ye, Li-Song Chen   +7 more
doaj   +1 more source

Deep Understanding of Vaginal Microbiota in HPV‐Related Diseases From a Multi‐Omics Perspective

VIEW Medicine, Volume 1, Issue 1, November 2026.
Current understanding of the vaginal microbiota and roles of critical vaginal bacteria, including Lactobacillus and anaerobic pathogens, in human papillomavirus (HPV) infection and HPV‐related diseases from a multi‐omics perspective. ABSTRACT There is a large number of microorganisms in the human body, which are inseparable from human health.
Jianxujie Zheng, Qing Cong, Ling Lin, Liang Qiao   +3 more
wiley   +1 more source