Results 31 to 40 of about 121,257 (309)

Stability and Antiglycoxidant Potential of Bilberry Anthocyanins in Simulated Gastrointestinal Tract Model

open access: yesFoods, 2020
Anthocyanins from Vaccinium myrtillus fruits have been reported in vitro to exert potent radical scavenging and antiglycation activities. However, the physiological relevance of such properties remains unclear given the potential susceptibility of ...
Didier Fraisse   +3 more
doaj   +1 more source

Açaì (Euterpe oleracea) Extract Protects Human Erythrocytes from Age-Related Oxidative Stress

open access: yesCells, 2022
Aging is a process characterised by a general decline in physiological functions. The high bioavailability of reactive oxygen species (ROS) plays an important role in the aging rate.
Alessia Remigante   +8 more
doaj   +1 more source

An Electrochemical Chip to Monitor In Vitro Glycation of Proteins and Screening of Antiglycation Potential of Drugs

open access: yesPharmaceutics, 2020
Hyperglycemia and the production of advanced glycation end products (AGEs) are the primary factors for the development of chronic complications in diabetes.
Zeeshan A. Khan, Seungkyung Park
doaj   +1 more source

Influence of Lactose on the Maillard Reaction and Dehydroalanine-Mediated Protein Cross-Linking in Casein and Whey

open access: yesFoods, 2022
A liquid chromatography–mass spectrometry method based on multiple reaction monitoring (MRM) was developed for the simultaneous quantification of markers representing two potentially competing pathways, the Maillard reaction and the dehydroalanine ...
Søren D. Nielsen   +4 more
doaj   +1 more source

AGEs in human lens capsule promote the TGFβ2-mediated EMT of lens epithelial cells:Implications for age-associated fibrosis [PDF]

open access: yes, 2016
Proteins in basement membrane (BM) are long-lived and accumulate chemical modifications during aging; advanced glycation end-product (AGE) formation is one such modification. The human lens capsule is a BM secreted by lens epithelial cells. In this study,
Glomb, Marcus   +9 more
core   +1 more source

Recent Advances and the Potential for Clinical Use of Autofluorescence Detection of Extra-Ophthalmic Tissues [PDF]

open access: yes, 2020
The autofluorescence (AF) characteristics of endogenous fluorophores allow the label-free assessment and visualization of cells and tissues of the human body.
Aigner, Felix   +7 more
core   +1 more source

DJ-1 Acts as a Scavenger of α-Synuclein Oligomers and Restores Monomeric Glycated α-Synuclein

open access: yesBiomolecules, 2021
Glycation of α-synuclein (αSyn), as occurs with aging, has been linked to the progression of Parkinson’s disease (PD) through the promotion of advanced glycation end-products and the formation of toxic oligomers that cannot be properly cleared from ...
Tamr B. Atieh   +4 more
doaj   +1 more source

A new gender-specific model for skin autofluorescence risk stratification [PDF]

open access: yes, 2015
Advanced glycation endproducts (AGEs) are believed to play a significant role in the pathophysiology of a variety of diseases including diabetes and cardiovascular diseases.
Ahmad, MS   +4 more
core   +1 more source

Targeting RAGE prevents muscle wasting and prolongs survival in cancer cachexia [PDF]

open access: yes, 2020
Background: Cachexia, a multifactorial syndrome affecting more than 50% of patients with advanced cancer and responsible for ~20% of cancer-associated deaths, is still a poorly understood process without a standard cure available. Skeletal muscle atrophy
Chiappalupi, S.   +9 more
core   +1 more source

Increased Non-Enzymatic Glycation of Plasma Proteins and Hemoglobin in Non-Diabetic Patients with Acute Myocardial Infarction (MI) [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Background: Glycation is known to play a key role in complications of many pathophysiological processes. The present study was carried out to assess whether there are abnormalities of non-enzymatic glycation of proteins and hemoglobin in acute ...
V. Parthibane   +4 more
doaj   +1 more source

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