Results 51 to 60 of about 4,588 (217)

Development in Maillard Reaction and Dehydroalanine Pathway Markers during Storage of UHT Milk Representing Differences in Casein Micelle Size and Sedimentation

Foods, 2022
Ultra-high temperature (UHT) processing of milk can result in protein changes during storage; however, the progress of dehydroalanine (DHA) mediated protein cross-linking and Maillard reactions in relation to the sediment formation have not been ...
Miguel Aguilera-Toro, Nina Aagaard Poulsen, Marije Akkerman, Valentin Rauh, Lotte Bach Larsen, Søren Drud-Heydary Nielsen   +5 more
doaj   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

Advanced Science, EarlyView.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao, Zhibin Zhou, Yuxuan Wei, Xiangfan Huang, Zhiyong Zhou, Jiaheng Chen, Haoxin Cheng, Xiaotian Hu, Xiaolei Wang   +8 more
wiley   +1 more source

LC-Orbitrap-MS/MS Analysis of Chosen Glycation Products in Infant Formulas

Molecules
When breastfeeding is not possible, infant formulas may be used instead of human milk. However, harmful advanced glycation end-products (AGEs) may be formed during thermal processing of infant formulas.
Aleksandra Damasiewicz-Bodzek, Magdalena Szumska, Agnieszka Nowak, Sławomir Waligóra, Beata Pastuszka, Kamila Stopińska, Beata Janoszka   +6 more
doaj   +1 more source

Glycated Haemoglobin Analysis [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1997
Haemoglobin (Hb) in the adult human consists of predominantly HbA, with a small amount of HbA2, and a trace of HbF. HbA contains a number of minor haemoglobins identified as HbAla, HbA1b, and HbA!c, collectively referred to as HbA l, 'fast haemoglobins', glycosylated or glycated haemoglobins or simply glycohaemoglobins.
openaire   +2 more sources

A Review of Glycated Albumin as an Intermediate Glycation Index for Controlling Diabetes [PDF]

Journal of Diabetes Science and Technology, 2008
Introduction: This article reviews glycated albumin (GA) as a potential intermediate-term glycation index to fill the gap between self-monitoring of blood glucose (SMBG) and hemoglobin A1c testing in diabetes management.
H Vernon, Roohk, Asad R, Zaidi
openaire   +2 more sources

S100A8/A9‐High Macrophages Activate Intestinal Fibroblasts via mCCL6/hCCL15‐CCR1 Axis to Drive Intestinal Fibrosis in Crohn's Disease

Advanced Science, EarlyView.
S100A8/A9‐high macrophages are markedly enriched in the stenotic intestinal tissue of patients with Crohn's disease. These profibrotic macrophages secrete mCCL6 in a STAT3‐dependent manner. mCCL6 and its human ortholog hCCL15 activate fibroblasts via the CCR1 receptor, thereby driving excessive collagen deposition.
Shu Wang, Jiayun Wang, Junjie Lin, Ziping Ye, Geyujia Zhou, Jingjing Ma, Junjian Sun, Jiang Yu, Yingdi Zhang, Nana Tang, Chunhua Jiao, Xiaojing Zhao, Hongjie Zhang   +12 more
wiley   +1 more source

Molecular mechanism of ischemic postconditioning in promoting diabetic ischemic brain injury repair via the microRNA‐34a–BDNF–SIX3 signaling axis

Animal Models and Experimental Medicine, EarlyView.
Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao, Chunlan Zou, Junxian Li, Yang Yang, Yuanyuan Han, Tingyu Ke   +5 more
wiley   +1 more source

Estimation of oxidative stress markers: human advanced glycation end products and human advanced oxidation protein products in patients with atopic dermatitis

Journal of the Egyptian Women’s Dermatologic Society
Introduction Pathogenesis of atopic dermatitis (AD) is complex and includes several aspects, such as genetics and environmental exposure. Recently, several research studies have highlighted the effect of oxidative stress (OS) in different dermatological ...
Iman M. Abdelmeniem, Aliaa I. Ismail, Naglaa F. Agamia, Nesrine A. Helaly, Hassan Mamdouh, Mohamed H. AbouHadeed, Dalia I. Halwag   +6 more
doaj   +1 more source

Ex vivo instability of glycated albumin: A role for autoxidative glycation [PDF]

Archives of Biochemistry and Biophysics, 2017
Ex vivo protein modifications occur within plasma and serum (P/S) samples due to prolonged exposure to the thawed state-which includes temperatures above -30 °C. Herein, the ex vivo glycation of human serum albumin from healthy and diabetic subjects was monitored in P/S samples stored for hours to months at -80 °C, -20 °C, and room temperature, as well
Joshua W. Jeffs, Shadi Ferdosi, Hussein N. Yassine, Chad R. Borges   +3 more
openaire   +2 more sources

UHPLC–MS based metabolomics study of the ErZhi formula on skeletal muscle against osteosarcopenia focusing on energy metabolism

Animal Models and Experimental Medicine, EarlyView.
ErZhi formula (EZF) is composed of Ligustri Lucidi Fructus (LLF) and Ecliptae herba (EH). Ovariectomized (OVX) and sham rats received 12‐week intragastric treatment with EZF, alendronate, and vehicle saline. Gastrocnemius tissues were harvested to systematically evaluate pharmacodynamic changes in skeletal muscle morphology, mitochondrial ...
Yuqing Pang, Ningning Li, Yujie Ding, Shuzhen Hou, Jing Liu, Xiuxue Liu, Erwei Liu, Xiaopeng Chen   +7 more
wiley   +1 more source