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Nrf2 and Oxidative Stress: A General Overview of Mechanisms and Implications in Human Disease

open access: yesAntioxidants, 2022
Organisms are continually exposed to exogenous and endogenous sources of reactive oxygen species (ROS) and other oxidants that have both beneficial and deleterious effects on the cell.
Vy Ngo, M. Duennwald
semanticscholar   +3 more sources

The influence of duration on pain stress, oxidative stress, and total antioxidant power status in female dogs undergoing ovariohysterectomy [PDF]

open access: yesVeterinary World, 2020
Background and Aim: Ovariohysterectomy (OHE) is a common procedure for sterilization of female dogs. However, knowledge of changes in pain stress, oxidative stress, and total antioxidant power status before, during, and after OHE is limited.
Kanissarinn Sakundech   +4 more
doaj   +1 more source

Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging

open access: yesArchives of Toxicology, 2023
A physiological level of oxygen/nitrogen free radicals and non-radical reactive species (collectively known as ROS/RNS) is termed oxidative eustress or “good stress” and is characterized by low to mild levels of oxidants involved in the regulation of ...
K. Jomová   +6 more
semanticscholar   +1 more source

Targeting oxidative stress in disease: promise and limitations of antioxidant therapy

open access: yesNature reviews. Drug discovery, 2021
Oxidative stress is a component of many diseases, including atherosclerosis, chronic obstructive pulmonary disease, Alzheimer disease and cancer.
H. Forman, Hong-Qiao Zhang
semanticscholar   +1 more source

Cardiovascular characterisation of a novel mouse model that combines hypertension and diabetes co-morbidities

open access: yesScientific Reports, 2023
Epidemiologic data suggest that the prevalence of hypertension in patients with diabetes mellitus is ∼1.5–2.0 times greater than in matched non-diabetic patients.
Arpeeta Sharma   +10 more
doaj   +1 more source

Chloroplast-derived photo-oxidative stress causes changes in H2O2 and EGSH in other subcellular compartments

open access: yesbioRxiv, 2020
Metabolic fluctuations in chloroplasts and mitochondria can trigger retrograde signals to modify nuclear gene expression. Mobile signals likely to be involved are reactive oxygen species (ROS), which can operate protein redox switches by oxidation of ...
J. Ugalde   +9 more
semanticscholar   +1 more source

A stress-blinded Atf1 can fully assemble heterochromatin in a RNAi-independent minimal mat locus but impairs directionality of mat2/3 switching

open access: yesiScience, 2022
Summary: The MAP kinase Sty1 phosphorylates and activates the transcription factor Atf1 in response to several stress conditions, which then shifts from a transcriptional repressor to an activator.
Rodrigo Fraile   +4 more
doaj   +1 more source

The Mediterranean diet and lifestyle [PDF]

open access: yesArhiv za farmaciju, 2023
The Mediterranean Diet (MedDiet) is characterized by a high intake of fruit, vegetables, whole grains, legumes, and olive oil, moderate consumption of poultry and fish, and a limited intake of red meat and minimal processed foods.
García-Hernández Silvia   +3 more
doaj   +1 more source

Dexamethasone increased the survival rate in Plasmodium berghei-infected mice

open access: yesScientific Reports, 2021
The present study aimed to evaluate the effects of dexamethasone on the redox status, parasitemia evolution, and survival rate of Plasmodium berghei-infected mice.
Danilo Reymão Moreira   +7 more
doaj   +1 more source

Polyunsaturated and Saturated Oxylipin Plasma Levels Allow Monitoring the Non-Alcoholic Fatty Liver Disease Progression to Severe Stages

open access: yesAntioxidants, 2023
Hepatic fat accumulation is the hallmark of non-alcoholic fatty liver disease (NAFLD). Our aim was to determine the plasma levels of oxylipins, free polyunsaturated fatty acids (PUFA) and markers of lipid peroxidation in patients with NAFLD in ...
Miguel D. Ferrer   +12 more
doaj   +1 more source

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