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Best Practice & Research Clinical Obstetrics & Gynaecology, 2011 Considerable evidence implicates oxidative stress in the pathophysiology of many complications of human pregnancy, and this topic has now become a major focus of both clinical and basic science research. Oxidative stress arises when the production of reactive oxygen species overwhelms the intrinsic anti-oxidant defences.
Burton, Graham J., Jauniaux, Eric
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Oxidative Stress: Harms and Benefits for Human Health
Oxidative Medicine and Cellular Longevity, 2017 Oxidative stress is a phenomenon caused by an imbalance between production and accumulation of oxygen reactive species (ROS) in cells and tissues and the ability of a biological system to detoxify these reactive products.
G. Pizzino +8 more
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Mechanisms of Oxidative Stress in Metabolic Syndrome
International Journal of Molecular Sciences, 2023 Metabolic syndrome is a cluster of conditions associated with the risk of diabetes mellitus type 2 and cardiovascular diseases (CVDs). Metabolic syndrome is closely related to obesity. Increased adiposity promotes inflammation and oxidative stress, which
S. Masenga +3 more
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Antagonistic effects of mitochondrial matrix and intermembrane space proteases on yeast aging
BMC Biology, 2022 Background In many organisms, aging is characterized by a loss of mitochondrial homeostasis. Multiple factors such as respiratory metabolism, mitochondrial fusion/fission, or mitophagy have been linked to cell longevity, but the exact impact of each one ...
Montserrat Vega +6 more
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Antioxidants, 2022 Metabolic syndrome (MetS) is characterized by increased pro-oxidative stress and a pro-inflammatory state. Several studies emphasized the protective effect of the Mediterranean dietary pattern (MDP).
Maria Magdalena Quetglas-Llabrés +7 more
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Oxidative Stress in Liver Pathophysiology and Disease
Antioxidants, 2023 The liver is an organ that is particularly exposed to reactive oxygen species (ROS), which not only arise during metabolic functions but also during the biotransformation of xenobiotics.
A. Allameh +4 more
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The Peroxisome in Oxidative Stress [PDF]
IUBMB Life, 2001 AbstractPeroxisomes are one of the main sites in the cell where oxygen free radicals are both generated and scavenged. The balance between these two processes is believed to be of great importance for proper functioning of cells and has been implicated in aging and carcinogenesis.
Dansen, T.B., Wirtz, K.W.A.
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Oxidative stress and inflammation in diabetic nephropathy: role of polyphenols
Frontiers in Immunology, 2023 Diabetic nephropathy (DN) often leads to end-stage renal disease. Oxidative stress demonstrates a crucial act in the onset and progression of DN, which triggers various pathological processes while promoting the activation of inflammation and forming a ...
Qi Jin +9 more
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Sarcopenia and peripheral arterial disease: a systematic review
Journal of Cachexia, Sarcopenia and Muscle, 2020 Background Patients with lower extremity peripheral arterial disease (PAD) and sarcopenia are a population at risk requiring specific and targeted care.
Mégane Pizzimenti +6 more
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The role of oxidative stress in diabetes mellitus-induced vascular endothelial dysfunction
Cardiovascular Diabetology, 2023 Diabetes mellitus is a metabolic disease characterized by long-term hyperglycaemia, which leads to microangiopathy and macroangiopathy and ultimately increases the mortality of diabetic patients.
Ying An +6 more
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