Results 41 to 50 of about 8,422,559 (217)
BACKGROUND: The involvement of free radicals and oxidative stress in HIV infection has been extensively studied, and the benefits of antioxidant supplementation in animal studies have been demonstrated. However, few studies have demonstrated a benefit in
Marcela S Figueira +9 more
doaj +1 more source
The NRF2, Thioredoxin, and Glutathione System in Tumorigenesis and Anticancer Therapies
Cancer remains an elusive, highly complex disease and a global burden. Constant change by acquired mutations and metabolic reprogramming contribute to the high inter- and intratumor heterogeneity of malignant cells, their selective growth advantage, and ...
Morana Jaganjac +3 more
doaj +1 more source
Non-alcoholic fatty liver disease (NAFLD) shows liver fat depots without alcohol consumption. NAFLD does not have specific drug therapies, with a healthy lifestyle and weight loss being the main approaches to prevent and treat NAFLD.
Maria Magdalena Quetglas-Llabrés +9 more
doaj +1 more source
BRCA1 and Oxidative Stress [PDF]
The breast cancer susceptibility gene 1 (BRCA1) has been well established as a tumor suppressor and functions primarily by maintaining genome integrity. Genome stability is compromised when cells are exposed to oxidative stress. Increasing evidence suggests that BRCA1 regulates oxidative stress and this may be another mechanism in preventing ...
Yi, Yong Weon, Kang, Hyo Jin, Bae, Insoo
openaire +2 more sources
An Overview of Oxidative Stress, Neuroinflammation, and Neurodegenerative Diseases
Oxidative stress has been linked with a variety of diseases, being involved in the debut and/or progress of several neurodegenerative disorders. This review intends to summarize some of the findings that correlate the overproduction of reactive oxygen ...
D. Teleanu +8 more
semanticscholar +1 more source
Non-alcoholic fatty liver disease (NAFLD) is a disorder characterized by the excessive accumulation of lipids in the liver parenchyma. To date, there is no effective pharmacological treatment against NAFLD.
Margalida Monserrat-Mesquida +11 more
doaj +1 more source
Oxidative stress and pesticide disease: a challenge for toxicology
Introduction: In the past decades, the synthesis of chemical compounds has resulted in a high number of substances used to protect crops from pests. Most pesticides have been used in large quantities for agricultural purposes. Acute and chronic poisoning
Sandra Catalina Cortés-Iza +1 more
doaj +1 more source
Assessing Food Preferences and Neophobias among Spanish Adolescents from Castilla–La Mancha
Food neophobia is a reaction of dislike or fear of food, which may be due to a wide variety of factors (taste, texture, exposure at an early age, genetics, or diversity in feeding practices and food consumption).
Carmen del Campo +3 more
doaj +1 more source
Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in response to
Mercè Carmona +8 more
doaj +1 more source
Summary: Cells have developed protein quality-control strategies to manage the accumulation of misfolded substrates during heat stress. Using a soluble reporter of misfolding in fission yeast, Rho1.C17R-GFP, we demonstrate that upon mild heat shock, the ...
Margarita Cabrera +6 more
doaj +1 more source

