Results 61 to 70 of about 8,422,559 (217)

Distinct roles of histone H2B ubiquitination at promoters and coding regions of Pol II-transcribed stress genes

open access: yesGenome Biology
Background The histone code, comprised of diverse histone post-translational modifications, intricately regulates nucleosome organization and gene expression. Histone marks also serve as binding sites for a diverse array of protein complexes and enzymes,
Rubén Barrios   +7 more
doaj   +1 more source

Factors affecting the intervention to increase the biosecurity levels of poultry production clusters (PPCs) in Thailand [PDF]

open access: yesResearch & Knowledge, 2016
The purpose of this study is to investigate the factors affecting the intervention to increase the biosecurity levels of poultry farms in Nong Khai province, Thailand. Research participants were 80 farms from three districts.
Worapol Aengwanich   +2 more
doaj   +1 more source

Effect of Ginger on Inflammatory Diseases

open access: yesMolecules, 2022
Ulcerative colitis, Crohn’s disease, rheumatoid arthritis, psoriasis, and lupus erythematosus are some of common inflammatory diseases. These affections are highly disabling and share signals such as inflammatory sequences and immune dysregulation.
Pura Ballester   +5 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Oxidative Stress in Cancer

open access: yesCancer Cell, 2020
Contingent upon concentration, reactive oxygen species (ROS) influence cancer evolution in apparently contradictory ways, either initiating/stimulating tumorigenesis and supporting transformation/proliferation of cancer cells or causing cell death.
J. Hayes, A. Dinkova-Kostova, K. Tew
semanticscholar   +1 more source

The Role of Oxidative Stress in Atherosclerosis

open access: yesCells, 2022
Atherosclerosis is a chronic inflammatory disease of the vascular system and is the leading cause of cardiovascular diseases worldwide. Excessive generation of reactive oxygen species (ROS) leads to a state of oxidative stress which is a major risk ...
Matthew Batty, M. Bennett, Emma P. K. Yu
semanticscholar   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Oxidative Stress in Ageing and Chronic Degenerative Pathologies: Molecular Mechanisms Involved in Counteracting Oxidative Stress and Chronic Inflammation

open access: yesInternational Journal of Molecular Sciences, 2022
Ageing and chronic degenerative pathologies demonstrate the shared characteristics of high bioavailability of reactive oxygen species (ROS) and oxidative stress, chronic/persistent inflammation, glycation, and mitochondrial abnormalities.
Thobekile S Leyane, S. Jere, N. Houreld
semanticscholar   +1 more source

Editorial on Anticancer Antioxidants

open access: yesAntioxidants, 2021
The current concepts of biomedicine consider oxidative stress to be one of crucial pathophysiological processes behind major stress- and age-associated diseases, including cancer [...]
Suzana Borovic Sunjic, Neven Zarkovic
doaj   +1 more source

Effect of Physical Activity/Exercise on Oxidative Stress and Inflammation in Muscle and Vascular Aging

open access: yesInternational Journal of Molecular Sciences, 2022
Functional status is considered the main determinant of healthy aging. Impairment in skeletal muscle and the cardiovascular system, two interrelated systems, results in compromised functional status in aging.
M. El Assar   +4 more
semanticscholar   +1 more source

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