Results 71 to 80 of about 1,220,550 (219)

Nrm1 is a bistable switch connecting cell cycle progression to transcriptional control

EMBO Reports
Entry into the cell cycle requires activation of G1 cyclin-dependent kinases (CDKs) and the G1/S transcriptional program. In fission yeast, the MBF complex is the main transcription factor driving early cell-cycle gene expression.
Guillem Murciano-Julià, Montserrat Vega, Esther Pazo, Àlex Pascual-Serra, Isabel Alves-Rodrigues, Oriol Bagudanch, Roger Anglada, Núria Bonet, Rosa Aligué, Sergio Moreno, Baldo Oliva, Elena Hidalgo, José Ayté   +12 more
doaj   +1 more source

Implications for oxidative stress and astrocytes following 26S proteasomal depletion in mouse forebrain neurones [PDF]

, 2013
Neurodegenerative diseases are characterized by progressive degeneration of selective neurones in the nervous system, but the underlying mechanisms involved in neuroprotection and neurodegeneration remain unclear.
Elkharaz, J, Billett, E, Ugun-Klusek, Aslihan, Bedford, L, Bedford, Lynn, Mayer, R John, Lowe, James, Mayer, RJ, Elkharaz, Jamal, Billett, Ellen, Lawler, K, Lawler, Karen, Ugun-Klusek, A, Lowe, J, Constantin-Teodosiu, D, Constantin-Teodosiu, Dumitru   +15 more
core   +1 more source

Oxidative Stress in Preterm Newborns [PDF]

, 2021
Preterm babies are highly susceptible to oxidative stress (OS) due to an imbalance between the oxidant and antioxidant systems. The generation of free radicals (FR) induces oxidative damage to multiple body organs and systems.
Serafina Perrone, Chiara Lembo, Giuseppe Buonocore   +2 more
core   +1 more source

Effects of Regular Exercise on the Biochemical, Oxidative, and Inflammatory Profiles and Quality of Life in Older Spaniards with Metabolic Syndrome

Antioxidants
Metabolic syndrome increases the risk of developing diabetes and cardiovascular disease. The regular practice of physical activity is a crucial factor for healthy aging and for controlling and preventing chronic diseases. To assess the effects of regular
Margalida Monserrat-Mesquida, Maria Magdalena Quetglas-Llabrés, Cristina Bouzas, Silvia García, David Mateos, Lucía Ugarriza, Cristina Gómez, Josep A. Tur, Antoni Sureda   +8 more
doaj   +1 more source

Mancozeb impairs mitochondrial and bioenergetic activity in Drosophila melanogaster

Heliyon, 2021
Mancozeb (MZ) is a broad-spectrum fungicide used worldwide in several crops. Neurological disorders in humans and animals have been associated with exposure to this compound by mechanisms still not fully understood.
Miriane Acosta Saraiva, Nelson Rodrigues de Carvalho, Illana Kemmerich Martins, Giulianna Echeverria Macedo, Nathane Rosa Rodrigues, Patrícia de Brum Vieira, Marina Prigol, Karen Kich Gomes, Cynthia Camila Ziech, Jeferson Luis Franco, Thais Posser   +10 more
doaj   +1 more source

Oxidative stress in otosclerosis [PDF]

Redox Report, 2016
Otosclerosis is a disease involving abnormal bone turnover in the human otic capsule that results in hearing loss. Several hypotheses have been suggested for the etiopathogenesis of otosclerosis; however, its etiology remains unclear.This study evaluated the correlation between otosclerosis and levels of paraoxonase-1 (PON1), arylesterase, total ...
Elif, Baysal, Secaattin, Gulsen, Ismail, Aytac, Fatih, Celenk, Nuray, Ensari, Seyithan, Taysi, Habib, Binici, Cengiz, Durucu, Semih, Mumbuc, Muzaffer, Kanlikama   +9 more
openaire   +2 more sources

Impact of Adherence to the Mediterranean Diet on Antioxidant Status and Metabolic Parameters in NAFLD Patients: A 24-Month Lifestyle Intervention Study

Antioxidants
Background: The Mediterranean Diet (MedDiet) is recognized as a healthy dietary pattern. Non-alcoholic fatty liver disease (NAFLD) is characterized by the excessive accumulation of fat in the liver.
Maria Magdalena Quetglas-Llabrés, Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, Emma Argelich, Miguel Casares, Lucía Ugarriza, Isabel Llompart, Josep A. Tur, Antoni Sureda   +9 more
doaj   +1 more source

Hyperinsulinemia and oxidative stress

Physiological Research, 2002
The aim of the study was to compare the effect of short-term hyperglycemia and short-term hyperinsulinemia on parameters of oxidative stress in Wistar rats. Twenty male rats (aged 3 months, average body weight 325 g) were tested by hyperinsulinemic clamp (100 IU/l) at two different glycemia levels (6 and 12 mmol/l).
P, Kyselová, M, Zourek, Z, Rusavý, L, Trefil, J, Racek   +4 more
openaire   +2 more sources

Oxidative Stress and Age-Related Tumors [PDF]

Oxidative stress is the result of the imbalance between reactive oxygen and nitrogen species (RONS), which are produced by several endogenous and exogenous processes, and antioxidant defenses consisting of exogenous and endogenous molecules that protect ...
Carlo Sorrentino, Emma Di Carlo
core   +1 more source

Two-Year Mediterranean Diet Intervention Improves Hepatic Health in MASLD Patients

Foods
Background: Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) is one of the leading causes of chronic liver disease, affecting 30% of the global adult population and continuing to rise.
Margalida Monserrat-Mesquida, Cristina Bouzas, Silvia García, David Mateos, Miguel Casares, Lucía Ugarriza, Cristina Gómez, Antoni Sureda, Josep A. Tur   +8 more
doaj   +1 more source