Results 41 to 50 of about 89,718 (303)

Impact of Enhanced Phagocytosis of Glycated Erythrocytes on Human Endothelial Cell Functions

open access: yesCells, 2022
Diabetes is associated with a high mortality rate due to vascular complications. Chronic hyperglycemia in diabetes leads to enhanced oxidative stress and glycation.
Chloé Turpin   +10 more
doaj   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali   +4 more
wiley   +1 more source

Failure of Common Glycation Assays to Detect Glycation by Fructose

open access: yesClinical Chemistry, 1992
Abstract Serum albumin was modified by in vitro glycation with either fructose or glucose, to see whether the common clinical assays for glycation were able to detect both fructose- and glucose-induced changes in protein structure in diabetes.
N, Ahmed, A J, Furth
openaire   +2 more sources

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu   +4 more
wiley   +1 more source

Exploring Glyoxalase Strategies for Managing Sugar-Induced Chronic Diseases

open access: yesLife
The liver’s crucial role in methylglyoxal (MG) metabolism is frequently overlooked in the literature. We present a perspective that enhances the current understanding of the role of methylglyoxal (MG) and the glyoxalase cycle in the pathogenesis of ...
Alejandro Gugliucci
doaj   +1 more source

Dietary Advanced Glycation End Products: Their Role in the Insulin Resistance of Aging

open access: yesCells, 2023
Insulin resistance (IR) is commonly observed during aging and is at the root of many of the chronic nontransmissible diseases experienced as people grow older. Many factors may play a role in causing IR, but diet is undoubtedly an important one.
Manuel Portero-Otin   +2 more
doaj   +1 more source

Advanced Materials for Biologics Delivery to Brain Tumors

open access: yesAdvanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng   +4 more
wiley   +1 more source

Scalable Fabrication of Chemically Stabilized Gelatin Hydrogel Fibers by Thermal Drawing

open access: yesAdvanced Materials Interfaces, EarlyView.
Scalable processing of hydrogel fibers remains a major challenge. By coupling thermal drawing with Maillard chemistry, a transient viscous‐flow window is created that enables continuous fabrication of microstructured gelatin fibers tens of meters long, while continued in situ crosslinking during drawing stabilizes the fibers for physiological ...
Chaoqun Dong   +5 more
wiley   +1 more source

KARAKTERISTIK KIMIA KONJUGAT ISOLAT PROTEIN KEDELAI-LAKTOSA YANG BERPOTENSI DALAM PENURUNAN ALERGENISITAS

open access: yesJurnal Teknologi dan Industri Pangan, 2018
Soy protein isolate (SPI) is a product of soybeans possessing good functionality thus it is widely used as an ingredient in any formulation in food and beverage industries.
Muhammad Hasriandy Asyhari   +2 more
doaj   +1 more source

Glycation and a Spark of ALEs (Advanced Lipoxidation End Products) – Igniting RAGE/Diaphanous-1 and Cardiometabolic Disease

open access: yesFrontiers in Cardiovascular Medicine, 2022
Obesity and non-alcoholic fatty liver disease (NAFLD) are on the rise world-wide; despite fervent advocacy for healthier diets and enhanced physical activity, these disorders persist unabated and, long-term, are major causes of morbidity and mortality ...
Lakshmi Arivazhagan   +4 more
doaj   +1 more source

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