Results 41 to 50 of about 4,588 (217)

Insights on glycated albumin

open access: yesAnnales de Biologie Clinique, 2019
Like all proteins, plasma albumin can undergo glycation to produce glycated albumin. This glycation will change the structure and therefore functionalities of albumin. Because of its accessibility, its high concentration and its half-life the glycation of albumin is greater than that of haemoglobin.
Anne, Hay-Lombardie   +2 more
openaire   +3 more sources

Glycation is regulated by isoflavones [PDF]

open access: yesFood Funct., 2014
The soy isoflavone-rich extract inhibitsin vitroformation ofNε-carboxymethyl-lysine (CML).
Silván, José Manuel   +3 more
openaire   +3 more sources

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

open access: yesAdvanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu   +13 more
wiley   +1 more source

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

open access: yesAdvanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu   +12 more
wiley   +1 more source

Integrated assessment of phytochemicals, Antilipase, hemoglobin antiglycation, antihyperglycemic, antifungal and antibacterial properties of vetiveria zizanioides (L.) Nash

open access: yesInternational Journal of Food Properties
Vetiveria zizanioides, known as vetiver grass, is renowned for its ecological significance in soil erosion control and the restoration of lands polluted by heavy metals.
Fahd Kandsi   +10 more
doaj   +1 more source

The AGE-RAGE Axis: Implications for Age-Associated Arterial Diseases

open access: yesFrontiers in Genetics, 2017
The process of advanced glycation leads to the generation and accumulation of an heterogeneous class of molecules called advanced glycation endproducts, or AGEs.
Laura M. Senatus, Ann Marie Schmidt
doaj   +1 more source

Albumin Abundance and Its Glycation Status Determine Hemoglobin Glycation [PDF]

open access: yesACS Omega, 2018
Diabetes diagnosis and management majorly depend upon the measurement of glycated hemoglobin (HbA1c) levels. Various factors influence HbA1c levels such as the use of various analytical methods and the presence of various clinical conditions. Plasma albumin levels were known to be negatively associated with HbA1c.
Mashanipalya G. Jagadeeshaprasad   +3 more
openaire   +3 more sources

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

open access: yesAdvanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li   +7 more
wiley   +1 more source

Oral Supplementation of Ozonated Sunflower Oil Augments Plasma Antioxidant and Anti-Inflammatory Abilities with Enhancement of High-Density Lipoproteins Functionality in Rats

open access: yesAntioxidants
Research on ozonated sunflower oil (OSO) is mostly restricted to its topical application, whereas the functional and toxicological assessment of oral OSO consumption is yet to be solved. Herein, OSO was orally supplemented in rats to assess the impact on
Kyung-Hyun Cho   +3 more
doaj   +1 more source

The effect of advanced glycation end products on cellular signaling molecules in skeletal muscle

open access: yesJournal of Physical Fitness and Sports Medicine, 2018
The accumulation of advanced glycation end products (AGEs) in the body causes the pathogenesis of aging-related diseases by inhibiting the normal properties and functions of proteins and the modulation of cellular signal transduction.
Tatsuro Egawa   +6 more
doaj   +1 more source

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