Results 61 to 70 of about 87,156 (304)

Insights on glycated albumin

Annales de Biologie Clinique, 2019
Like all proteins, plasma albumin can undergo glycation to produce glycated albumin. This glycation will change the structure and therefore functionalities of albumin. Because of its accessibility, its high concentration and its half-life the glycation of albumin is greater than that of haemoglobin.
Anne, Hay-Lombardie, Saïd, Kamel, Edith, Bigot-Corbel   +2 more
openaire   +3 more sources

Glycation is regulated by isoflavones [PDF]

Food & Function, 2014
The soy isoflavone-rich extract inhibits in vitro formation of N ε -carboxymethyl-lysine (CML).
Silván, José Manuel, Srey, Chou, Ames, Jennifer M., Castillo, M. Dolores del   +3 more
openaire   +3 more sources

Metabolic Memory in Cardiovascular Disease: Encoding, Propagation, and Therapeutic Targeting

Advanced Science, EarlyView.
Cardiovascular risk often persists after metabolic abnormalities are corrected. This conceptual Review frames such persistence as metabolic memory, encoded through a narrowing therapeutic window from reversible marks to irreversible damage, with continuous input from peripheral organs.
Cheng Cheng, Minghui Tang, Zhaobo Zhang, Ruoyi Qu, Jianfei Pei, Tian Liu, Siyao Qu, Shilong You, Shenshen Cui, Wenke Wang, Rui Zhao, Yingxian Sun, Naijin Zhang   +12 more
wiley   +1 more source

Oral Supplementation of Ozonated Sunflower Oil Augments Plasma Antioxidant and Anti-Inflammatory Abilities with Enhancement of High-Density Lipoproteins Functionality in Rats

Antioxidants
Research on ozonated sunflower oil (OSO) is mostly restricted to its topical application, whereas the functional and toxicological assessment of oral OSO consumption is yet to be solved. Herein, OSO was orally supplemented in rats to assess the impact on
Kyung-Hyun Cho, Ji-Eun Kim, Myeong-Sung Lee, Ashutosh Bahuguna   +3 more
doaj   +1 more source

The effect of advanced glycation end products on cellular signaling molecules in skeletal muscle

Journal of Physical Fitness and Sports Medicine, 2018
The accumulation of advanced glycation end products (AGEs) in the body causes the pathogenesis of aging-related diseases by inhibiting the normal properties and functions of proteins and the modulation of cellular signal transduction.
Tatsuro Egawa, Yoshitaka Ohno, Shingo Yokoyama, Ayumi Goto, Rika Ito, Tatsuya Hayashi, Katsumasa Goto   +6 more
doaj   +1 more source

Development in Maillard Reaction and Dehydroalanine Pathway Markers during Storage of UHT Milk Representing Differences in Casein Micelle Size and Sedimentation

Foods, 2022
Ultra-high temperature (UHT) processing of milk can result in protein changes during storage; however, the progress of dehydroalanine (DHA) mediated protein cross-linking and Maillard reactions in relation to the sediment formation have not been ...
Miguel Aguilera-Toro, Nina Aagaard Poulsen, Marije Akkerman, Valentin Rauh, Lotte Bach Larsen, Søren Drud-Heydary Nielsen   +5 more
doaj   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

Both Ca2+ and Zn2+ are essential for S100A12 protein oligomerization and function [PDF]

, 2009
Background Human S100A12 is a member of the S100 family of EF-hand calcium-modulated proteins that are associated with many diseases including cancer, chronic inflammation and neurological disorders.
Lednev, Igor K., Helmut Wittkowski, Anatoli Ianoul, Igor B Bronstein, Shekhtman, Alexander, Bjoerk, Per, Alexander Shekhtman, Per Bjoerk, Foell, Dirk, Wei He, Igor K Lednev, Olga V Moroz, He, Wei, Burkitt, William I., Xie, Jingjing, Derrick, Peter J., Bronstein, Igor B., Vera Novitskaya, Polyakova, Oxana, Ianoul, Anatoli, Dirk Foell, Will Burkitt, Oxana Polyakova, Moroz, Olga V., Peter J Derrick, Wittkowski, Helmut, Novitskaya, Vera, Jingjing Xie   +27 more
core   +1 more source

D-ribose in glycation and protein aggregation [PDF]

, 2012
Background: D-ribose is a naturally occurring pentose monosaccharide present in all living cells and their microenvironments and is a key component of numerous biomolecules involved in many important metabolic pathways.
Liu, Ying, Wei, Yan, Zhou, Jun, He, Rong Qiao, He, RQ (reprint author), Chinese Acad Sci, Inst Biophys, State Key Lab Brain & Cognit Sci, 15 Datun Rd, Beijing 100101, Peoples R China., Han, Chan Shuai, Chen, Lan   +6 more
core   +1 more source

LC-Orbitrap-MS/MS Analysis of Chosen Glycation Products in Infant Formulas

Molecules
When breastfeeding is not possible, infant formulas may be used instead of human milk. However, harmful advanced glycation end-products (AGEs) may be formed during thermal processing of infant formulas.
Aleksandra Damasiewicz-Bodzek, Magdalena Szumska, Agnieszka Nowak, Sławomir Waligóra, Beata Pastuszka, Kamila Stopińska, Beata Janoszka   +6 more
doaj   +1 more source