Results 11 to 20 of about 9,264,964 (263)

Exploring the Interactions Between Caffeic Acid and Human Serum Albumin Using Spectroscopic and Molecular Docking Techniques [PDF]

, 2021
Ultraviolet-visible (UV–Vis) and fluorescence spectroscopy along with molecular docking were used to explore the interaction between human serum albumin (HSA) and caffeic acid (CA).
Jahanban Esfahlan, Ali, Lorenzo Rodríguez, José Manuel, Roufegarinejad, Leila, Tabibiazar, Mahnaz, Amarowicz, Ryszard, José Lorenzo, Ali Jahanban-Esfahlan, Mahnaz Tabibiazar, José M. Lorenzo, Ryszard Amarowicz, Leila Roufegarinejad   +10 more
core   +2 more sources

Allosteric modulation of zinc speciation by fatty acids [PDF]

, 2013
Background: Serum albumin is the major protein component of blood plasma and is responsible for the circulatory transport of a range of small molecules that include fatty acids, hormones, metal ions and drugs.
Barnett, James P., Sadler, Peter J., Stewart, Alan J., Blindauer, Claudia A., Martin, Esther M., Khazaipoul, Siavash, Kassaar, Omar, Sadler, P. J., Stewart, Alan J. S., Barnett, James P., Dr., Stewart, Alan J.; id_orcid   +10 more
core   +2 more sources

Carboxylated Poly-l-Lysine as a Macromolecular Cryoprotective Agent Enables the Development of Defined and Xeno-Free Human Sperm Cryopreservation Reagents

Cells, 2021
In human sperm cryopreservation, test yolk buffer and human serum albumin have been used as permeating macromolecular-weight cryoprotectants. In clinical reproductive medicine, human serum albumin is frequently used because of low risks of zoonoses and ...
Hiroki Takeuchi, Mikiko Nishioka, Tadashi Maezawa, Yuko Kitano, Kento Terada-Yoshikawa, Ryota Tachibana, Manabu Kato, Suong-hyu Hyon, Yuki Gen, Kayo Tanaka, Kuniaki Toriyabe, Masafumi Nii, Eiji Kondo, Tomoaki Ikeda   +13 more
doaj   +1 more source

Study of Interactions of an Anticancer Drug Neratinib With Bovine Serum Albumin: Spectroscopic and Molecular Docking Approach

Frontiers in Chemistry, 2018
Binding of therapeutic agents to plasma proteins, particularly to serum albumin, provides valuable information in the drug development. This study was designed to evaluate the binding interaction of neratinib with bovine serum albumin (BSA).
Tanveer A. Wani, Ahmed H. Bakheit, Ahmed H. Bakheit, M. A. Abounassif, Seema Zargar   +4 more
doaj   +1 more source

A simple colorimetric assay to determine the concentration and proportion of human mercaptalbumin

Practical Laboratory Medicine, 2022
Objectives: Human serum albumin can take on two forms, mercaptalbumin (HMA) or non-mercaptalbumin (HNA), depending on the redox status of its Cys34. The ratio of HMA and HNA is considered to be a novel biomarker of oxidative stress.
Sawaki Tada, Keiko Yasukawa, Yutaka Yatomi, Tomoaki Uchiki   +3 more
doaj   +1 more source

Allosteric inhibition of cobalt binding to albumin by fatty acids : implications for the detection of myocardial ischemia [PDF]

, 2012
The biomarker "ischemia-modified albumin" (IMA), measured by the albumin-cobalt-binding assay (ACB assay), is the only FDA-approved biomarker for early diagnosis of myocardial ischemia.
Peter J. Sadler, Sadler, P. J., Sadler, Peter J., Claudia A. Blindauer, Teresa J. T. Pinheiro, Stewart, Alan J., Blindauer, Claudia A., Pinheiro, Teresa J. T., Jin Lu, Lu, Jin, Alan J. Stewart, Stewart, Alan J.; id_orcid   +11 more
core   +1 more source

Study of binding interaction of rivaroxaban with bovine serum albumin using multi-spectroscopic and molecular docking approach

Chemistry Central Journal, 2017
Background Rivaroxaban is a direct inhibitor of coagulation factor Xa and is used for venous thromboembolic disorders. The rivaroxaban interaction with BSA was studied to understand its PK and PD (pharmacokinetics and pharmacokinetics) properties.
Tanveer A. Wani, Haitham AlRabiah, Ahmed H. Bakheit, Mohd Abul Kalam, Seema Zargar   +4 more
doaj   +1 more source

Surface imprinted beads for the recognition of human serum albumin [PDF]

, 2007
The synthesis of poly-aminophenylboronic acid (ABPA) imprinted beads for the recognition of the protein human serum albumin (HSA) is reported. In order to create homogeneous recognition sites, covalent immobilisation of the template HSA was exploited.
Bossi, Alessandra,, Turner, Anthony P. F., Piletsky S., Turner A. P. F., Speghini, Adolfo,, Piletsky, Sergey,, Speghini, Adolfo, BOSSI, Alessandra Maria, P. F. Turner, Anthony,, Bossi, Alessandra, Bonini, Francesca,, Piletsky, Sergey A., Bonini F., Bonini, Francesca   +13 more
core   +1 more source

Preoperative Risk Factors for Predicting Postoperative Human Serum Albumin Infusion after Hip Fracture Surgery: Development and Validation of a Nomogram

Balkan Medical Journal, 2023
Background: As one of the adverse events after hip fracture surgery, hypoalbuminemia is usually treated using human serum albumin infusion. However, the application of human serum albumin may cause complications such as postsurgical infection and ...
Xiao Chen, Xin Liu, Junpeng Pan, Penzhou You, Sijun Ren   +4 more
doaj   +1 more source

Plasma free fatty acid levels influence Zn2+-dependent histidine-rich glycoprotein-heparin interactions via an allosteric switch on serum albumin [PDF]

, 2014
Background: Histidine-rich glycoprotein (HRG) regulates coagulation, through its ability to bind and neutralize heparins. HRG associates with zinc ions (Zn2+) to stimulate HRG-heparin complex formation. Under normal conditions the majority of plasma Zn2+
Schwarz-Linek, Ulrich, Blindauer, Claudia A, Stewart, Alan J., Blindauer, Claudia A., Kassaar, Omar, Schwarz-Linek, Ulrich; id_orcid, Stewart, Alan J.; id_orcid   +6 more
core   +1 more source