Results 41 to 50 of about 9,264,964 (263)

Human Serum Albumin and Human Serum Albumin Nanoparticles as Carriers of 10-(2′-Pyrimidyl)-3,6-diazaphenothiazine: In Vitro Spectroscopic Studies

Molecules
Human serum albumin (HSA) plays a fundamental role in the human body, including the transport of exogenous and endogenous substances. HSA is also a biopolymer with a great medical and pharmaceutical potential.
Aleksandra Owczarzy, Karolina Kulig, Beata Morak-Młodawska, Małgorzata Jeleń, Tammam Muhammetoglu, Wojciech Rogóż, Małgorzata Maciążek-Jurczyk   +6 more
doaj   +1 more source

Anionic Calixarene-Capped Silver Nanoparticles Show Species-Dependent Binding to Serum Albumins

Molecules, 2013
The anionic calixarenes para-sulphonatocalix[4]arene and 1,3-di-Ophosphonatocalix[ 4]arene, have been used to cap silver nanoparticles. The binding of these functional particles with regard to various serum albumins (bovine serum albumin, human serum ...
Anthony W. Coleman, Florent Perret, Arnaud Brioude, Beomjoon Kim, Yannick Tauran   +4 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Bilirubin-human serum albumin interaction monitored by capillary zone electrophoresis

, 1999
Capillary zone electrophoresis was used to monitor the interaction between bilirubin and human serum albumin. Cord blood serum samples were injected directly into an uncoated fused-silica capillary (30 cm x 50 μm i.d.) and separation was accomplished ...
Lau, KM, Fung, Y, Fung, YS, Zhang, B, Lin, B, Lau, K, Lin, BC, Kapman Lau, Bingcheng Lin, Yingsing Fung, Bin Zhang   +10 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Extraction and Purification of albumin from Hunan plasma

مجلة بغداد للعلوم, 2011
This study includes adescription of Human serum Albumin by amodified using ion- exchange chromatography with manipulated comparison with cold ethanol precipitation method , It has been nticed that this procedure is superior orer the classical method ...
Baghdad Science Journal
doaj   +1 more source

Novel Post-translational Modifications in Human Serum Albumin

, 2022
Aim: This study aims to identify novel post-translational modifications in human serum albumin by mass spectrometry. Background: Serum albumin is the most abundant protein in plasma, has many physiological functions, and is in contact with most of the ...
Kannan, Surya, Souchelnytskyi, Serhiy, Krishnankutty, Roopesh   +2 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

SWCNT Network-FET Device for Human Serum Albumin Detection

Sensors, 2022
A thin film of single-walled carbon nanotube (SWCNT) network field-effect transistor (FET) was fabricated by a simple, fast, and reliable deposition method for electronic applications.
Iskandar Yahya, Muhamad Azuddin Hassan, Nur Nasyifa Mohd Maidin, Mohd Ambri Mohamed   +3 more
doaj   +1 more source