Results 61 to 70 of about 9,264,964 (263)

Interaction of anticancer reduced Schiff base coumarin derivatives with human serum albumin investigated by fluorescence quenching and molecular modeling [PDF]

, 2014
The specific binding of five reduced Schiff base derived 7-amino-coumarin compounds with antitumor activity to human serum albumin, the principal binding protein of blood, was studied by fluorescence spectroscopy.
Enyedy Éva Anna, Dömötör, Orsolya, Karcz, Darius, Enyedy E., Tuccinardi Tiziano, Dömötör O, Walsh M, Karcz Darius, Enyedy, Éva Anna, Tuccinardi, Tiziano, Karcz D, Walsh Maureen, Dömötör Orsolya, Creaven Bernadette S., Creaven BS   +14 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Molecular Interaction between a Gadolinium-Polyoxometalate and Human Serum Albumin

, 2009
Polyoxometalates (POMs) show promising antibacterial, antiviral (particularly anti-HIV), antitumor, and anticancer activities, but the mechanism of these potential therapeutic effects remains to be elucidated at the molecular level.
de Oliveira, Pedro, Miron, Simona, Zheng, Li, Nadjo, Louis, Craescu, Constantin T., Ma, Ying, Kortz, Ulrich, Zhang, Guangjin, Zhang, GJ, Keita, Bineta, Bassil, Bassem S., Yao, Jiannian, Li Zheng, Guangjin Zhang, Jiannian Yao, Louis Nadjo, Ulrich Kortz, Bassem S. Bassil, Constantin T. Craescu, Pedro de Oliveira, Simona Miron, Ying Ma, Bineta Keita   +22 more
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Trypsinized human serum containing albumin potentiates fibrocyte differentiation.

, 2013
(A) TPCK-treated trypsin-coated agarose beads were used to digest human serum and albumin-depleted human serum, which were then added to PBMC in protein-free media at the indicated concentrations for 5 days, after which the cells were air-dried, stained,
Richard H. Gomer (214653), Michael J. V. White (443102), Melissa Glenn (443103)   +2 more
core   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Interaction of cimetidine with human serum albumin

, 1990
Ultrafiltration studies have detected the existence of a weak interaction between cimetidine and human serum albumin, a finding supported by corresponding studies with this xenobiotic and bovine serum albumin.
Bogoyevitch, Marie A., Wilson, Craig J., Winzor, Donald J.   +2 more
core   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Selective extraction of flavonoids from Ginkgo biloba leaves using human serum albumin functionalized magnetic nanoparticles [PDF]

, 2013
In a novel procedure, human serum albumin functionalized magnetic nanoparticles (HSA-MNPs) were used to selectively extract nine flavonoids in the extract of Ginkgo biloba leaves.
Liang, J, Xue, Y, Liao, X, Ding, LS, Ren, XY   +4 more
core  

The Relationships among Serum Glucose, Albumin Concentrations and Carotid Atherosclerosis in Men with Spinal Cord Injury

, 2010
Limited information is available that examines the interrelationships between glucose tolerance, serum albumin, subclinical inflammation, and carotid atherosclerosis (CA) in patients with spinal cord injury (SCI).
WANG, YEN-HO;CHEN, SSU-YUAN;WANG, TZUNG -DAU;HWANG, BAO-SHOW;HUANG, TIEN-SHANG;SU, TA-CHEN, 王顏和;陳思遠;王宗道;黃寶秀;黃天祥;蘇大成   +1 more
core   +1 more source