Results 51 to 60 of about 1,355,358 (352)
Absence of the CXCR4 antagonist EPI-X4 from pharmaceutical human serum albumin preparations
Journal of Translational Medicine, 2021 Background Endogenous Peptide Inhibitor of CXCR4 (EPI-X4) is a natural antagonist of the CXC chemokine receptor 4 (CXCR4). EPI-X4 is a 16-mer peptide that is released from human serum albumin (HSA) by acidic aspartic proteases such as Cathepsin D and E ...
Andrea Gilg +5 more
doaj +1 more source
Polyamine Analogues Bind Human Serum Albumin [PDF]
Biomacromolecules, 2007 Polyamine analogues show antitumor activity in experimental models, and their ability to alter activity of cytotoxic chemotherapeutic agents in breast cancer is well documented. Association of polyamines with nucleic acids and protein is included in their mechanism of action.
R, Beauchemin +5 more
openaire +2 more sources
Serum albumin and beta-amyloid deposition in the human brain
Neurology, 2020 Objectives To investigate the relationships of serum albumin with in vivo Alzheimer disease (AD) pathologies, including cerebral β-amyloid (Aβ) protein deposition, neurodegeneration of AD-signature regions, and cerebral white matter hyperintensities (WMH)
Jee Wook Kim +11 more
semanticscholar +1 more source
Overview of Albumin and Its Purification Methods [PDF]
Advanced Pharmaceutical Bulletin, 2016 As the most frequent plasma protein, albumin constitutes more than 50% of the serum proteins in healthy individuals. It has a key role in oncotic pressure maintenance and it is known as a versatile protein carrier for transportation of various endogenous
Ramin Raoufinia +5 more
doaj +1 more source
Journal of Clinical Medicine, 2023 Serum albumin (ALB), one of the most important proteins in human physiology, has the main functions of maintaining plasma oncotic pressure and plasma volume, transporting hormones, vitamins, oligominerals and drugs, and exerting a powerful antioxidant ...
E. Gremese +5 more
semanticscholar +1 more source
Interaction of Citrinin with Human Serum Albumin
Toxins, 2015 Citrinin (CIT) is a mycotoxin produced by several Aspergillus, Penicillium, and Monascus species. CIT occurs worldwide in different foods and drinks and causes health problems for humans and animals.
Miklós Poór +6 more
doaj +1 more source
A new approach to immunoFET operation [PDF]
, 1990 A new method is presented for the detection of an immunological reaction taking place in a membrane, which covers the gate area of an ISFET. By stepwise changing the electrolyte concentration of the sample solution, a transient diffusion of ions through ...
Bergveld, P. +3 more
core +2 more sources
Binding of 99mTc to human serum albumin
Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2004 The specificity of 99m Tc-MDP binding to HSA was examined , the results showed that the non specific binding was 21-23% of the total binding . The range of optimum pH for the binding was 7.4-7.6 .
Abdulrahman K. Loay
doaj +1 more source
Antioxidants, 2021 Cardiovascular disorders, especially acute coronary syndromes, are among the leading causes of mortality worldwide, and advanced glycation end products (AGEs) are associated with cardiovascular disease and serve as biomarkers for diagnosis and prediction.
Govigerel Bayarsaikhan +4 more
doaj +1 more source
Acta Pharmaceutica Sinica B, 2017 The blood–brain barrier (BBB) and the poor ability of many drugs to cross that barrier greatly limits the efficacy of chemotherapies for glioblastoma multiforme (GBM).
Chunhui Ruan +10 more
semanticscholar +1 more source