Results 71 to 80 of about 9,264,964 (263)

3D depictions of docking of 5g in the active site of human serum albumin.

open access: yes, 2023
3D depictions of docking of 5g in the active site of human serum albumin.
Afnan M. Alnajeebi (14559602)   +12 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Hydroxyurea-Loaded Albumin Nanoparticles: Preparation, Characterization, and In Vitro Studies

open access: yesPharmaceutics, 2019
Human serum albumin nanoparticles (HSA-NPs) have been widely used as drug delivery systems. In most cases, HSA-NPs are formed by the method of desolvation in the presence of glutaraldehyde as a crosslinking agent.
Yerkeblan Tazhbayev   +3 more
doaj   +1 more source

POTENTIAL IMPACTS OF PHARMACEUTICAL USES OF TRANSGENIC TOBACCO: THE CASE OF HUMAN SERUM ALBUMIN (HSA) [PDF]

open access: yes
The potential size and distribution of benefits from transgenic tobacco as a source of human serum albumin are estimated using an economic surplus model with imperfect competition.
Kostandini, Genti   +2 more
core  

Adsorption of human serum albumin onto gold: a combined electrochemical and ellipsometric study

open access: yes, 2004
Human serum albumin adsorption onto gold surfaces was investigated by electrochemical and ellipsometric methods. Albumin adsorption onto gold was confirmed by the change of the open circuit potential of gold and by the ellipsometric parameter variation ...
应佩青   +4 more
core   +1 more source

3D depictions of 5e docking in the active site of human serum albumin.

open access: yes, 2023
3D depictions of 5e docking in the active site of human serum albumin.
Afnan M. Alnajeebi (14559602)   +12 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Effect of Papaverine on Human Serum Albumin Glycation

open access: yesJournal of Medicinal Plants, 2012
Background: Glycation is a non enzymatic reaction initiated by the primary addition of sugar to the amino groups of proteins.In the early stage of glyction, the synthesis of intermediates leading to formation of Amadori compounds occurs.
A Ahmadzadeh, M Feizie, R Ghafarzadegan
doaj  

2D depiction of docking of 5e in the active site of human serum albumin.

open access: yes, 2023
2D depiction of docking of 5e in the active site of human serum albumin.
Afnan M. Alnajeebi (14559602)   +12 more
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

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