Results 171 to 180 of about 156,444 (266)

Development and Validation of a Questionnaire‐Based Model for Households With Multiple Helicobacter pylori Infections: A Family‐Based Screening Strategy

open access: yesMed Research, EarlyView.
This study developed and externally validated a questionnaire‐based household risk model to identify families with multiple Helicobacter pylori infections. Using only noninvasive, readily available household information, the model showed good discrimination and enabled a family‐based screening strategy that substantially improved detection efficiency ...
Yifan Qiu   +9 more
wiley   +1 more source

MAML1 drives Notch and Hedgehog oncogenic pathways by inhibiting Itch activity in triple-negative breast cancer. [PDF]

open access: yesCell Death Differ
Zema S   +23 more
europepmc   +1 more source

Speech and Deep Brain Stimulation in Parkinson's Disease, Essential Tremor, and Dystonia: A Systematic Review and Meta‐analysis

open access: yesMovement Disorders, EarlyView.
Abstract Deep brain stimulation (DBS) effectively treats motor symptoms in movement disorders but often compromises speech through incompletely defined mechanisms. We conducted a PROSPERO‐registered systematic review and meta‐analysis of publications through August 2024 (CRD42024527738).
Elina Tripoliti   +15 more
wiley   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek   +3 more
wiley   +1 more source

In Vivo Auto-tuning of Antibody-Drug Conjugate Delivery to Maximize Efficacy Using High-Avidity, Low-Affinity Antibodies. [PDF]

open access: yesMol Cancer Ther
Kopp A   +9 more
europepmc   +1 more source

Extending the hyper‐logistic model to the random setting: New theoretical results with real‐world applications

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
We develop a full randomization of the classical hyper‐logistic growth model by obtaining closed‐form expressions for relevant quantities of interest, such as the first probability density function of its solution, the time until a given fixed population is reached, and the population at the inflection point.
Juan Carlos Cortés   +2 more
wiley   +1 more source

Comparative Outcomes of Fine Needle Aspiration and Core Needle Biopsy for Parotid Masses

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the diagnostic accuracy and safety of ultrasound‐guided fine needle aspiration (FNA) versus core needle biopsy (CNB) for parotid masses. Study Design Retrospective cohort study. Setting Tertiary academic medical center, 2018 to 2023. Methods We reviewed 485 patients undergoing ultrasound‐guided parotid biopsy (426 FNAs and
Lisa Eleni Chionis Buhler   +8 more
wiley   +1 more source

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