Results 191 to 200 of about 3,337,131 (281)

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek   +3 more
wiley   +1 more source

Extending the hyper‐logistic model to the random setting: New theoretical results with real‐world applications

open access: yesMathematical Methods in the Applied Sciences, EarlyView.
We develop a full randomization of the classical hyper‐logistic growth model by obtaining closed‐form expressions for relevant quantities of interest, such as the first probability density function of its solution, the time until a given fixed population is reached, and the population at the inflection point.
Juan Carlos Cortés   +2 more
wiley   +1 more source

AAV capsid sites breakdown: large protein insertions impact on vector dynamics. [PDF]

open access: yesFront Bioeng Biotechnol
Ferreira MV   +8 more
europepmc   +1 more source

Machine Learning‐Assisted Optimization for Dynamic Supply Network Design in the Additive Manufacturing Platform

open access: yesNaval Research Logistics (NRL), EarlyView.
ABSTRACT Distributed manufacturing enabled by additive manufacturing (AM) allows supply chains to rapidly adapt to changing market conditions through flexible facility relocation and capacity adjustment. However, existing studies largely overlook the logistical aspects of AM‐based supply chains and typically treat facility location and logistics ...
Behrang Bootaki, Guoqing Zhang
wiley   +1 more source

A structured multidisciplinary home parenteral nutrition program in a public healthcare system: Implementation model, nursing‐led training protocol, and 11‐year safety outcomes

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Home parenteral nutrition (HPN) is the standard of care for adults with chronic intestinal failure (CIF), but evidence from publicly funded healthcare systems in middle‐income countries is limited. This study describes an 11‐year experience of a structured, nursing‐led HPN program within Brazil's Unified Health System (SUS ...
Tatiana da Cunha Rana   +5 more
wiley   +1 more source

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