Results 61 to 70 of about 2,568,206 (333)

Robust design of semi-automated clustering models for 4D-STEM datasets

APL Machine Learning, 2023
Materials discovery and design require characterizing material structures at the nanometer and sub-nanometer scale. Four-Dimensional Scanning Transmission Electron Microscopy (4D-STEM) resolves the crystal structure of materials, but many 4D-STEM data ...
Alexandra Bruefach, Colin Ophus, M. C. Scott   +2 more
doaj   +1 more source

Direct Versus Indirect Measurement of Digit Ratio (2D:4D): A Critical Review of the Literature and New Data

, 2016
Digit ratio (2D:4D: the relative lengths of the second and fourth digits) is widely used as a correlate of prenatal sex steroids. There are two common methods of measuring 2D:4D, the direct method and the indirect method.
Manning, John, John T. Manning, Neave, Nick, Ribeiro, Evaldo, Rosana N. Morais, Evaldo Ribeiro, Nick Neave, Morais, Rosana   +7 more
core   +1 more source

Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons [PDF]

, 2014
In the postnatal and adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs), the myelinating cells of the CNS.
Raineteau, Olivier, Fischer, Bruno,, Sommer, Lukas, Sommer, Lukas,, Draganova, Kalina,, Draganova, Kalina, Fischer, Bruno, Cantu, Claudio, Azim, Kasum,, Butt, Arthur, Raineteau, Olivier,, Butt, Arthur,, Azim, Kasum, Hurtado-Chong, Anahi,, Hurtado-Chong, Anahi, Cantù, Claudio,, Zemke, Martina, Zemke, Martina,   +17 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

D-STEM: a Design led approach to STEM innovation [PDF]

, 2014
Advances in the Science, Technology, Engineering and Maths (STEM) disciplines offer opportunities for designers to propose and make products with advanced, enhanced and engineered properties and functionalities.
Toomey, Anne, Kapsali, Veronika
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Digit ratio (2D:4D) and gender inequalities across nations

, 2014
Gender inequality varies across nations, where such inequality is defined as the disproportionate representation of one sex over the other in desirable social, economic, and biological roles (typically male over female).
Manning, John, John T. Manning, Trivers, Robert, Bernhard Fink, Fink, Bernhard, Robert Trivers   +5 more
core   +1 more source

Activities of the Loja W-STEM node

, 2021
The 3rd meeting of the W-STEM ERASMUS + Capacity-building in Higher Education European Project (Ref. 598923-EPP-1-2018-1-ES-EPPKA2-CBHE-JP) had scheduled to be held in Guadalajara (Mexico). The COVID-19 pandemic did not allow us to meet face-to-face, and
Loja W-STEM node
core   +1 more source

Robust Local Thickness Estimation of Sub‐Micrometer Specimen by 4D‐STEM

Small Methods, 2023
Abstract A quantitative four‐dimensional scanning transmission electron microscopy (4D‐STEM) imaging technique (q4STEM) for local thickness estimation across amorphous specimen such as obtained by focused ion beam (FIB)‐milling of lamellae for (cryo‐)TEM analysis is presented.
Skoupý, Radim, Boltje, Daan B., Slouf, Miroslav, Mrázová, Kateřina, Láznička, Tomáš, Taisne, Clémence M., Krzyžánek, Vladislav, Hoogenboom, Jacob P., Jakobi, Arjen J.   +8 more
openaire   +4 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source