Results 61 to 70 of about 1,029,481 (281)

Laws of 4D Printing

Engineering, 2020
The main difference between 3D and 4D printed structures is one extra dimension that is smart evolution over time. However, currently, there is no general formula to model and predict this extra dimension. Here, by starting from fundamental concepts, we derive and validate a universal bi-exponential formula that is required to model and predict the ...
Momeni, Farhang, Ni, Jun
openaire   +2 more sources

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unsynchronized 4D Barcodes [PDF]

, 2007
We present a novel technique for optical data transfer between public displays and mobile devices based on unsynchronized 4D barcodes. We assume that no direct (electromagnetic or other) connection between the devices can exist. Time-multiplexed, 2D color barcodes are displayed on screens and recorded with camera equipped mobile phones.
Langlotz, Tobias, Bimber, Oliver (Prof. Dr.)   +1 more
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Optimal LiDAR Data Resolution Analysis for Object Classification

Sensors, 2022
When classifying objects in 3D LiDAR data, it is important to use efficient collection methods and processing algorithms. This paper considers the resolution needed to classify 3D objects accurately and discusses how this resolution is accomplished for ...
Marjorie Darrah, Matthew Richardson, Bradley DeRoos, Mitchell Wathen   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Investigating the diffusion of 4D BIM Innovation [PDF]

, 2015
UK Government regularly applies challenging strategic targets to the construction industry, chief amongst these are requirements for more rapid project delivery processes and consistent improvements to the time predictability aspects of on-site ...
Gledson, Barry
core  

Formetric 4D Rasterstereography [PDF]

BioMed Research International, 2014
This paper is a comment on “Intra- and interday reliability of spine rasterstereography” [1]. We think that supporting the feasibility of using the rasterstereographic tool Formetric 4D, both as a diagnostic tool and in scientific research, requires much more scientific exactness.
Johnny Padulo, Luca Paolo Ardigò
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source