Results 71 to 80 of about 1,029,481 (281)

4D-GTWR

open access: yes, 2019
Geographically weighted regression model (GWR) and space-time geographically weighted regression model (GTWR) are constructed without considering the four-dimensional spatial-temporal heterogeneity.
NO Name (7492852)
core   +1 more source

The Visible Hand: Finger ratio (2D:4D) and competitive behavior [PDF]

open access: yes
In an experiment using two-bidder first-price sealed bid auctions with symmetric independent private values, we scan also the right hand of each subject.
Schipper, Burkhard C, Pearson, Matthew
core   +2 more sources

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

4D-STEM Ptychography for Electron-Beam-Sensitive Materials

open access: yes, 2022
Recent advances in high-speed pixelated electron detectors have substantially facilitated the implementation of four-dimensional scanning transmission electron microscopy (4D-STEM).
Guanxing Li (7309334)   +2 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Surveying the extent and use of 4D BIM in the UK [PDF]

open access: yes, 2016
More than half of construction projects exceed their agreed time schedules. Attempts to remedy this have been monitored over a number of years in the UK using standard industry KPI measurement data.
Greenwood, David, Gledson, Barry
core  

4D-seismic-neural-inversion

open access: yes, 2019
Deep Neural Networks for Map-Based 4D Seismic Pressure-Saturation ...
Jesper Soeren Dramsch (5622362)
core   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

4D-Multilayer-Modeler

open access: yes, 2022
Code from my 4D printing journal publication http://cad-journal.net/files/vol_20/CAD_20(3)_2023_489-506 ...
David E. Breen (14124861)   +1 more
core  

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