Results 71 to 80 of about 1,013,892 (284)
Formetric 4D Rasterstereography [PDF]
BioMed Research International, 2014 This paper is a comment on “Intra- and interday reliability of spine rasterstereography” [1]. We think that supporting the feasibility of using the rasterstereographic tool Formetric 4D, both as a diagnostic tool and in scientific research, requires much more scientific exactness.
Johnny Padulo, Luca Paolo Ardigò
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Visible Hand: Finger ratio (2D:4D) and competitive behavior [PDF]
In an experiment using two-bidder first-price sealed bid auctions with symmetric independent private values, we scan also the right hand of each subject.
Schipper, Burkhard C, Pearson, Matthew
core +2 more sources
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Pre-processed raw data of 4D-SCED 4D-STEM(NBD) datasets
, 2022 The raw 4D-SCED and 4D-STEM (NBD) datasets in our paper: Seeing Structural Evolution of Organic Molecular Nano-crystallites Using 4D Scanning Confocal Electron Diffraction https://arxiv.org/abs/2110.02373v1 Dose-damage_RT_and_Cryo_DRCN5T_PCBM.zip -
Harreiss, Christina, Wu, Mingjian
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
4D-STEM Ptychography for Electron-Beam-Sensitive Materials
, 2022 Recent advances in high-speed pixelated electron detectors have substantially facilitated the implementation of four-dimensional scanning transmission electron microscopy (4D-STEM).
Guanxing Li (7309334) +2 more
core +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
ORION-4D: OMC-1 C18O (6-5) cube + moment 0 map
Region: OMC-1 Lines: C18O (6-5) (7-6) (658.553 GHz) Resolution: 10" Type: On-The-Fly Nyquist-sampled map (mosaic) CUBE + MOM 0 Dimensions: ~ 450" x 200" Reference: Hacar et al 2020 (https://ui.adsabs.harvard.edu/abs/2020arXiv200912549H/abstract)
ORION-4D
core +1 more source