Results 91 to 100 of about 1,013,892 (284)

Genomics in 3D and 4D [PDF]

open access: yesNature Methods, 2016
DNA folding shapes gene expression. Emerging techniques promise to reveal the intricacies of this architectural language of chromosomes.
openaire   +2 more sources

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Scaling 4D Representations

open access: yesCoRR
Scaling has not yet been convincingly demonstrated for pure self-supervised learning from video. However, prior work has focused evaluations on semantic-related tasks $\unicode{x2013}$ action classification, ImageNet classification, etc. In this paper we focus on evaluating self-supervised learning on non-semantic vision tasks that are more spatial (3D)
João Carreira 0001   +34 more
openaire   +3 more sources

Castillo de Santa Magdalena de Pulpis

open access: yes, 2019
Proyecto geomático realizado por AD&D 4D para la Diputación de Castellónhttps://www.castellonarqueologico.es/yacimientos/el-baix-maestrat/castillo-santa-magdalena-de-pulpis/https://www.castellonarqueologico.es/va/yacimientos/el-baix-maestrat/castillo ...
Muñoz, Robert, AD&D 4D
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

INFIX/EXFIX: Massive Open Pelvic Injuries and Review of the Literature

open access: yesCase Reports in Orthopedics, 2016
Introduction. Open pelvic fractures make up 2–5% of all pelvic ring injuries. Their mortality has been reported to be as high as 50%. During Operation Enduring Freedom protocols for massive open pelvic injuries lead to the survival of injuries once ...
Rahul Vaidya   +5 more
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

4D-FLOW MRI: application in congenital heart disease studies [PDF]

open access: yes, 2022
openL'obiettivo della tesi è di approfondire una innovativa sequenza di risonanza magnetica, 4D-FLOW MRI, sia dal punto di vista tecnico sia analizzando i benefici che si possono ottenere dalla sua applicazione nella routine diagnostica e di follow-up ...
LUISON, KEVIN
core  

The Moon │Project │ STEM

open access: yes, 2019
Today, 3D has become a new and powerful form of expression, communication and knowledge transmission. With this powerful tool, the teacher will be able to articulate an attractive narrative and visual discourse.
NASA   +2 more
core   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

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