Results 91 to 100 of about 1,029,481 (281)

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

INFIX/EXFIX: Massive Open Pelvic Injuries and Review of the Literature

Case Reports in Orthopedics, 2016
Introduction. Open pelvic fractures make up 2–5% of all pelvic ring injuries. Their mortality has been reported to be as high as 50%. During Operation Enduring Freedom protocols for massive open pelvic injuries lead to the survival of injuries once ...
Rahul Vaidya, Kerellos Nasr, Enrique Feria-Arias, Rebecca Fisher, Marvin Kajy, Lawrence N. Diebel   +5 more
doaj   +1 more source

Instruct 4D-to-4D: Editing 4D Scenes as Pseudo-3D Scenes Using 2D Diffusion

2024 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR)
This paper proposes Instruct 4D-to-4D that achieves 4D awareness and spatial-temporal consistency for 2D diffusion models to generate high-quality instruction-guided dynamic scene editing results. Traditional applications of 2D diffusion models in dynamic scene editing often result in inconsistency, primarily due to their inherent frame-by-frame ...
Linzhan Mou, Jun-Kun Chen, Yu-Xiong Wang
openaire   +4 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

On skeletonization in 4D images [PDF]

, 1996
In this paper we extended the 3D Skeletonization method based on Euler number count & cluster count to 4D. As the Euler sum in 4D is always 0, we solved this by embedding 4D objects in a 5D space to calculate the 5D Euler number. The 5D Euler number changes due to 3 events: 1D tunnels, 2D tunnels and 3D tunnels.
Pieter Jonker, Obbe Vermeij
openaire   +2 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

4D Electron Tomography

Science, 2010
Temporal Tomography Tomography is a widely used technique for visualizing three-dimensional objects by algorithmic reconstruction from multiple two-dimensional images from distinct vantage points. However, its application has largely been restricted to static imaging. Kwon and Zewail
Kwon, Oh Hoon, Zewail, Ahmed H.
openaire   +3 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Fusing 4D modeling and laser scanning for automated construction progress control [PDF]

, 2010
The construction industry remains one of the riskiest of all. This risk is mainly the result of a poorly controlled, and thus uncertain, environment. For instance, construction progress is often improperly controlled, resulting in some unnoticed errors ...
Bosche, Frederic Nicolas, Haas, Carl T., Turkan, Yelda, Haas, Ralph   +3 more
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