Results 101 to 110 of about 1,029,481 (281)

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Capacity of Albit® Plant Growth Stimulator for Mitigating Side-effects of Pesticides on Soil Microbial Respiration

open access: yesJournal of Natural Resources and Development, 2017
Microorganisms give an early and integrated measure of soil functioning. In particular, soil microbial respiration is recommended for monitoring soil quality.
Natalia N. Karpun   +4 more
doaj   +1 more source

Scaling 4D Representations

open access: yesCoRR
Scaling has not yet been convincingly demonstrated for pure self-supervised learning from video. However, prior work has focused evaluations on semantic-related tasks $\unicode{x2013}$ action classification, ImageNet classification, etc. In this paper we focus on evaluating self-supervised learning on non-semantic vision tasks that are more spatial (3D)
João Carreira 0001   +34 more
openaire   +3 more sources

The 4D composite Higgs

open access: yesJournal of High Energy Physics, 2012
Abstract We propose a four dimensional description of Composite Higgs Models which represents a complete framework for the physics of the Higgs as a pseudo-Nambu-Goldstone boson. Our setup captures all the relevant features of 5D models and more in general of composite Higgs models with partial compositeness.
De Curtis, Stefania   +2 more
openaire   +2 more sources

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Innovative Online Diagnostic Assessment for Evaluating Science Learning Readiness in the Merdeka Curriculum Framework

open access: yesJournal of Education and Teaching
The main objective of this study was to develop an Online Diagnostic Assessment (ODA) that can effectively measure junior high school students’ readiness to learn science within the framework of the Merdeka Curriculum.
Widowati Pusporini   +4 more
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

4D-Polysense

open access: yes, 2018
Vídeo divulgatiu del projecte H2020 No.796292 4D-POLYPropylene meshes as SENsitive motion SEnsors (4D ...
Lanzalaco, Sonia
core  

Using 4D BIM in the Retrofit Process of Social Housing [PDF]

open access: yes, 2015
There is a large stock of solid wall homes in the UK presenting poor thermal insulation and low energy performance. Although the UK Government has supported improvement efforts in the area, the identification of appropriate technical solutions that ...
Formoso, Carlos   +3 more
core   +2 more sources

A 4D view on mRNA

open access: yesOncotarget, 2015
Imaging single molecules in live cells in 4+D (space, time and colors) is crucial for studying various biological processes, especially for observing the behavior of RNA molecules within the nuclear landscape [1]. RNA molecules are known to serve a multitude of tasks such as being templates for protein translation or to act as enzymes for regulating ...
Carlas, Smith   +2 more
openaire   +2 more sources

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