Results 111 to 120 of about 396,810 (295)
Four-dimensional flow provides incremental diagnostic value over echocardiography in aortic stenosis
Open HeartAims Four-dimensional flow cardiovascular MRI (4D flow CMR) has emerged as a promising technique for assessing aortic stenosis (AS). This study aimed to evaluate the agreement between 4D flow CMR and transthoracic echocardiography (TTE) in estimating ...Samer Alabed, Pankaj Garg, Rui Li, Julia Sun, John Curtin, Fabrizio Ricci, Andrew J Swift, Ciaran Grafton-Clarke, Peter Swoboda, David Hewson, Hosamadin Assadi, Rimma Hall, Vassilios S Vassiliou, Vasiliki Tsampasian, Gareth Matthews, Zia Mehmood, Bahman Kasmai, Gurung-Koney Yashoda, Rob J van der Geest, Sunil Nair, Laura Staff, Kurian Thampi, Jordi Broncano +22 moredoaj +1 more sourceSystemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim +6 morewiley +1 more sourceNoninvasive 4D pressure difference mapping derived from 4D flow MRI in patients with repaired aortic coarctation: comparison with young healthy volunteers
, 2015 To assess spatial and temporal pressure characteristics in patients with repaired aortic coarctation compared to young healthy volunteers using time-resolved velocity-encoded three-dimensional phase-contrast magnetic resonance imaging (4D flow MRI) and ...von Tengg-Kobligk, Hendrik, Ley-Zaporozhan, Julia, Delles, Michael, Unterhinninghofen, Roland, Ley, Sebastian, Tengg-Kobligk, Hendrik von, Eichhorn, Joachim, Dillmann, Rüdiger, Dillmann, Ruediger, Kauczor, Hans-Ulrich, Rengier, Fabian, Azad, Yoo-Jin +11 morecore +1 more sourceLarge‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco +11 morewiley +1 more source4D FLOW: Una nueva herramienta de diagnóstico para cardiopatías congénitas</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>Revista Chilena de Radiología</i>, 2011 </span><br><span class="r_content">Objetivo. Demostrar la utilidad de 4D flow para el análisis de patrones y distribución de flujos en pacientes con cardiopatías congénitas. Métodos: Seis pacientes con cardiopatías congénitas fueron escaneados con un protocolo de resonancia magnética ...</span><br><span class="r_sub"><i>Natalia Pinochet R<span id="ma_7" style="display:none">, Pablo Bächler S, Cristián Tejos N, Gerard Crelier, Rodrigo Parra R, José Miguel Allendes C, Pablo Irarrázaval M, Sergio Uribe A</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_7')">+7 more</a></small></i></span><br><small><a href="https://doaj.org/article/674550c914a24c758d3ed592bc6a1f69" target="_blank" rel="nofollow" title="doaj.org/article/674550c914a24c758d3ed592bc6a1f69">doaj</a> </small> <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1002/2211-5463.70240" target="_blank" rel="nofollow">Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>FEBS Open Bio, EarlyView.</i></span><br><span class="r_content">Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.</span><br><span class="r_sub"><i>Dong Seong Cho<span id="ma_8" style="display:none">, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_8')">+4 more</a></small></i></span><br><small><a href="https://onlinelibrary.wiley.com/doi/10.1002/2211-5463.70240?mi=2or9o2m&af=R&AllField=4d flow&ConceptID=15941&content=articlesChapters&target=default" target="_blank" rel="nofollow" title="wiley.com/doi/10.1002/2211-5463.70240?mi=2or9o2m&af=R&AllField=4d flow&ConceptID=15941&content=articlesChapters&target=default">wiley</a> </small> <div id="more_8" style="display:none"><a href="/sci_redir.php?doi=10.1002%2F2211-5463.70240" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1002/2211-5463.70240'); alert('Copied the doi');">copy doi</a> <small>(10.1002/2211-5463.70240)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_8')">+1 more source</a></small><br></div><div class="r"><p class="r_title"><a href="" target="_blank" rel="nofollow">4D flow MRI of Liver Hemodynamics: Influence of Velocity Encoding, Different Field Strength and Contrast Application on Visualization and Quantification of blood flow.</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16">, 2017 </span><br><span class="r_content">4D flow MRI offers the possibility for complete volumetric and functional assessment of liver blood flow in patients with liver cirrhosis. This study reveals a significant difference when using a lower venc for visualization of the portal vein branches ...</span><br><span class="r_sub"><i>Surla, Jelena<span id="ma_9" style="display:none">, Jung, Bernd, Peters, Alan Arthur, Stankovic, Zoran, Edouard, Semaan, Michael, Markl, Ith, Michael, Heverhagen, Johannes, Jeremy, Collins</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_9')">+8 more</a></small></i></span><br><small><a href="https://core.ac.uk/works/61547872" target="_blank" rel="nofollow" title="core.ac.uk/works/61547872">core</a> </small> <br></div><div class="r"><p class="r_title"><a href="https://doi.org/10.1371/journal.pone.0300709" target="_blank" rel="nofollow">Enhanced echocardiographic assessment of intracardiac flow in congenital heart disease.</a> </p><span class="r_subtitle"><img src="/img/openaccess.ico" alt="open access: yes" title="open access: yes" width="16" height="16"><i>PLoS ONE</i></span><br><span class="r_content">Background4D flow magnetic resonance imaging (4D flow MRI) can assess and measure the complex flow patterns of the right ventricle (RV) in congenital heart diseases, but its limited availability makes the broad application of intracardiac flow assessment </span><br><span class="r_sub"><i>Brett A Meyers<span id="ma_10" style="display:none">, Jiacheng Zhang, Jonathan Nyce, Yue-Hin Loke, Pavlos P Vlachos</span> <small><a href="#" style="color:#808080;" onClick="return toggle_div(this, 'ma_10')">+4 more</a></small></i></span><br><small><a href="https://doaj.org/article/e1f5482c19ee4cecac299e6641da0fd8" target="_blank" rel="nofollow" title="doaj.org/article/e1f5482c19ee4cecac299e6641da0fd8">doaj</a> </small> <div id="more_10" style="display:none"><a href="/sci_redir.php?doi=10.1371%2Fjournal.pone.0300709" target="_blank" rel="nofollow">openaccessbutton.org (pdf)</a><br><a href="javascript:navigator.clipboard.writeText('10.1371/journal.pone.0300709'); alert('Copied the doi');">copy doi</a> <small>(10.1371/journal.pone.0300709)</small><br></div><small><a href="#" onClick="return toggle_div(this, 'more_10')">+1 more source</a></small><br></div><div class="r"><div style="margin-bottom:2px;overflow:hidden"><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-magnetic_resonance_imaging/" class="suggestion"onclick="show_loader();"><b>magnetic resonance imaging</b></a><br/><a href="/q-blood_flow_velocity/" class="suggestion"onclick="show_loader();"><b>blood flow velocity</b></a><br/><a href="/q-humans/" class="suggestion"onclick="show_loader();"><b>humans</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-hemodynamics/" class="suggestion"onclick="show_loader();"><b>hemodynamics</b></a><br/><a href="/q-imaging%2C_three-dimensional/" class="suggestion"onclick="show_loader();"><b>imaging, three-dimensional</b></a><br/><a href="/q-4d_flow_mri/" class="suggestion"onclick="show_loader();"><b>4d flow mri</b></a><br/></div><div style="display: inline-block; float: left; font-size: small; padding-right: 16px; margin-top: -1px; padding-bottom: 1px;"><a href="/q-medicine/" class="suggestion"onclick="show_loader();"><b>medicine</b></a><br/><a href="/q-image_interpretation%2C_computer-assisted/" class="suggestion"onclick="show_loader();"><b>image interpretation, computer-assisted</b></a><br/><a href="/q-reproducibility_of_results/" class="suggestion"onclick="show_loader();"><b>reproducibility of results</b></a><br/></div></div></div><div class="pagenav"><a href="/q-4d_flow/p-11/" rel="nofollow"><b>previous</b></a> <a href="/q-4d_flow/p-10/" rel="nofollow">10</a> <a href="/q-4d_flow/p-11/" rel="nofollow">11</a> <b>12</b> <a href="/q-4d_flow/p-13/" rel="nofollow">13</a> <a href="/q-4d_flow/p-14/" rel="nofollow">14</a> <a href="/q-4d_flow/p-13/" id="next" rel="nofollow"><b>next</b></a> </div><br></div>
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