Results 91 to 100 of about 344,744 (207)
HYPERSENSITIVITY TO PARA-AMINOSALICYLIC ACID
, 1965 1. Attention is drawn to the incidence of hypersensitivity to para-aminosalicylic acid in the course of antituberculous treatment. 2. The clinical features are described with particular reference to hepatic complications. 3.
H. E. D. Griffiths, C. Watts
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The choice of treatment approach for mild and moderate ulcerative colitis: A review
Consilium MedicumUlcerative colitis (UC) is a chronic immune-inflammatory disease of unknown etiology characterized by continuous non-granulomatous inflammation of the colon mucosa. Inflammation may be limited to the rectum but often extends to the proximal colon.
Oleg V. Golovenko +2 more
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Inflammatory Mediators in Inflammatory Bowel Disease
Canadian Journal of Gastroenterology, 1990 Tissue responses to an inflammatory stimulus (such as vasodilation, plasma exudation invasion and activation of inflammatory cells) are elicited by locally synthesized chemical mediators.
BM Peskar
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, 2018 The aim of this study was to design and synthesize four colon-targeting mutual prodrugs of 5-aminosalicylic acid (5-ASA) and butyrate, and evaluate their therapeutic effects on ulcerative colitis.
Xianting Xie +6 more
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Design, Synthesis, and Testing of a Molecular Truck for Colonic Delivery of 5‑Aminosalicylic Acid
, 2016 A molecular scaffold bearing eight terminal alkyne groups was synthesized from sucrose. Eight copies of an azide-terminated, azo-linked precursor to 5-aminosalicylic acid were attached to the scaffold via copper(I)-catalyzed azide–alkyne cycloaddition ...
Ali M. Ahad (1903366) +7 more
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Design, Synthesis, and Testing of a Molecular Truck for Colonic Delivery of 5-Aminosalicylic Acid
, 2012 A molecular scaffold bearing eight terminal alkyne groups was synthesized from sucrose. Eight copies of an azide-terminated, azo-linked precursor to 5-aminosalicylic acid were attached to the scaffold via copper(I)-catalyzed azide–alkyne cycloaddition ...
Woodford, Rita Marie T. +7 more
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, 1993 5-Aminosalicylic acid (5-ASA) is the active principle of a number of preparations aimed at the treatment of inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis, but its efficacy is limited by early absorption and metabolism.
MARINOZZI, Maura +6 more
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, 2011 In recent years, many achievements have been realized in the therapy of inflammatory bowel disease (IBD) although its etiology remains unknown. Thus IBD treatment is symptomatic and targets general inflammatory mechanisms.
Rabišková, Miloslava +5 more
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Retrograde spread of 5-aminosalicylic acid enemas in patients with active ulcerative colitis
, 1986 n an attempt to know the exact retrograde spread of high-dosage 5-aminosalicylic acid enemas, we have studied eight patients with active left-sided colitis, by adding a small amount of barium sulfate to the enemas and by checking the spread ...
Bazzocchi G. +8 more
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NEW METABOLITES OF THE DRUG 5-AMINOSALICYLIC ACID .2. N-FORMYL-5-AMINOSALICYLIC ACID
, 1991 1. A new metabolite of the drug 5-aminosalicylic acid (5-ASA) has been found in urine from pigs and in plasma of humans. The metabolite has been isolated from pig urine using an XAD-2 column and purified using preparative h.p.l.c. 2.
Tjornelund, J. +2 more
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