Results 1 to 10 of about 14,789 (299)
Significance of the drug-induced lymphocyte stimulation test for various oral mesalamines in ulcerative colitis with mesalamine intolerance. [PDF]
PLoS ONEThis study aimed to determine if the drug-induced lymphocyte stimulation test (DLST) for various oral mesalamines can diagnose mesalamine intolerance and predict the success of retreatment in patients with adverse events (AEs) due to the first oral 5 ...
Akira Madarame +9 more
doaj +4 more sources
Frontiers in Pharmacology, 2021 Mesalamine has been well used in the improvement of ulcerative colitis (UC) in clinics, however, the underlying mechanisms were not well illustrated. To explore its efficacy from the perspective of gut microbiota and related metabolites, we employed 16S ...
Liang Dai, Yanqi Dang, Guang Ji
exaly +4 more sources
The Use and Role of Mesalamine in the Treatment of Ulcerative Colitis: A Literature Review. [PDF]
CureusOne of the most common forms of Inflammatory bowel disease amongst adolescents, with chronic relapsing and inflammation involving the colonic mucosa, is ulcerative colitis (UC).
Chand S +6 more
europepmc +4 more sources
Effectiveness of Mesalamine in Patients With Ulcerative Colitis: A Systematic Review [PDF]
Cureus, 2023 Ulcerative colitis (UC) management has changed significantly in the past decade. The goal is to treat the symptoms, aid tissue healing, and change the disease course to improve future outcomes.
Yurianna Santos, Arturo P Jaramillo
semanticscholar +2 more sources
Saudi Pharmaceutical Journal, 2023 Ulcerative colitis (UC) is an inflammatory condition of colon characterized by severe damage to the innermost colon tissues. A number of studies described the use of medication delivery systems based on natural polymers like polysaccharides for the ...
Imtiyaz Ahmed Najar +9 more
doaj +2 more sources
Risk of Hemolytic Anemia in IBD Patients with Glucose-6-Phosphate Dehydrogenase Deficiency Treated with Mesalamine: Results of a Retrospective-Prospective and Ex Vivo Study [PDF]
Journal of Clinical Medicine, 2023 Background: Mesalamine is one of the most-used drugs in inflammatory bowel disease (IBD), especially ulcerative colitis. Regulatory agencies have listed mesalamine as an unsafe drug in subjects with glucose-6-phosphate dehydrogenase (G6PD) deficiency ...
M. Dore +8 more
semanticscholar +2 more sources
Oxidation of Mesalamine under Phenoloxidase- or Peroxidase-like Enzyme Catalysis
Molecules, 2023 Mesalamine, also called 5-ASA (5-aminosalicylic acid), is a largely used anti-inflammatory agent and is a main choice to treat Ulcerative Colitis. This report is aimed to investigate enzymatic processes involved in the oxidation of mesalamine to better ...
Rimaz El Zein +4 more
doaj +2 more sources
Gels, 2023 This research aims to develop a drug delivery system that effectively treats colitis while administering curcumin/mesalamine by coating alginate/chitosan beads with Eudragit® S-100 to target the colon. Beads were tested to determine their physicochemical
Eman J. Heikal +8 more
doaj +2 more sources
Update on the management of ulcerative colitis: treatment and maintenance approaches focused on MMX® mesalamine [PDF]
, 2012 Ulcerative colitis (UC) is a chronic inflammatory disease of the colon that typically manifests as diarrhea, abdominal pain, and bloody stool. Complications, such as colorectal cancer and extraintestinal manifestations, may also develop.
Moss, Alan C., Nanda, Kavinderjit
core +3 more sources
American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2022 PURPOSE Necrotizing enterocolitis (NEC) remains a devastating disease that affects preterm infants. Hydrogen sulfide (H2S) donors have been shown to reduce the severity of NEC, but the optimal compound has yet to be identified.
B. Hosfield +7 more
semanticscholar +3 more sources