Results 31 to 40 of about 8,428 (249)

Genetic variants in cellular transport do not affect mesalamine response in ulcerative colitis. [PDF]

PLoS ONE, 2018
Mesalamine is commonly used to treat ulcerative colitis (UC). Although mesalamine acts topically, in vitro data suggest that intracellular transport is required for its beneficial effect.
Christopher J Moran, Hailiang Huang, Manuel Rivas, Jess L Kaplan, Mark J Daly, Harland S Winter   +5 more
doaj   +1 more source

Induction of oxidative DNA damage by mesalamine in the presence of copper: a potential mechanism for mesalamine anticancer activity [PDF]

, 2011
Mesalamine is the first line pharmacologic intervention for patients with ulcerative colitis, and recent epidemiologic studies have demonstrated a protective association between therapeutic use of the drug and colorectal carcinoma. However, the mechanism
Misra, H. P., Ryan P. Zimmerman, Zhu, Hong, Li, Y., Nathan Vandjelovic, Wang, J., Jia, Z., Zhu, H., Jianmin Wang, Yunbo Li, Vandjelovic, N., Zhenquan Jia, Hara P. Misra, Zimmerman, R. P., Li, Yunbo, Misra, Hara P, Wang, Jianmin, Jia, Zhenquan, Zimmerman, Ryan, Vandjelovic, Nathan, Hong Zhu   +20 more
core   +2 more sources

Efficacy and safety of two pH-dependent-release mesalamine doses in moderately active ulcerative colitis: a multicenter, randomized, double-blind, parallel-group study [PDF]

Intestinal Research, 2016
Background/AimsThe therapeutic effect of mesalamine is considered to be dose-dependent; however, no consensus has been reached regarding the optimal doses for individual patients.
Yasuo Suzuki, Mitsuo Iida, Hiroaki Ito, Isamu Saida, Toshifumi Hibi   +4 more
doaj   +1 more source

Recent advances in mesalamine colonic delivery systems

Future Journal of Pharmaceutical Sciences, 2020
Background Increased attention has been focused on the continuous development and improvement of mesalamine colonic specific delivery systems, for the effective treatment of inflammatory bowel diseases; thus enhancing therapeutic efficacy and reducing ...
Mohammad F. Bayan, Rana F. Bayan
doaj   +1 more source

A Case of Stevens–Johnson Syndrome Complicated with Multimatrix System Mesalamine in Ulcerative Colitis

Medicina, 2022
A 41-year-old man was treated with prednisolone (PSL) and multimatrix (MMX) mesalamine for remission induction therapy of ulcerative colitis. PSL was tapered due to successful remission induction treatment.
Mimari Kanazawa, Keiichi Tominaga, Akira Kanamori, Takanao Tanaka, Satoshi Masuyama, Shoko Watanabe, Keiichiro Abe, Akira Yamamiya, Kenichi Goda, Atsushi Irisawa   +9 more
doaj   +1 more source

Development of Novel pH-Sensitive Eudragit Coated Beads Containing Curcumin-Mesalamine Combination for Colon-Specific Drug Delivery

Gels, 2023
This research aims to develop a drug delivery system that effectively treats colitis while administering curcumin/mesalamine by coating alginate/chitosan beads with Eudragit® S-100 to target the colon. Beads were tested to determine their physicochemical
Eman J. Heikal, Rashad M. Kaoud, Shadeed Gad, Hatem I. Mokhtar, Abdullah Alattar, Reem Alshaman, Sawsan A. Zaitone, Yasser M. Moustafa, Taha M. Hammady   +8 more
doaj   +1 more source

Suppository treatment in ulcerative proctitis

European Journal of Inflammation, 2021
Ulcerative proctitis (UP) is a common form of ulcerative colitis (UC), the number of patients with UP is increasing. Suppository treatment containing mesalamine is usually the first-line choice for mild to moderate UP, here, we review the publications on
Yingjie Si, LanJun Shao, Shanqing Gao, Hongzhu Wen   +3 more
doaj   +1 more source

Successful management of HIV infection in a patient with ulcerative colitis; a case report [PDF]

Journal of Preventive Epidemiology, 2021
Human immunodeficiency virus (HIV) is an infectious disease that is rarely seen in ulcerative colitis patients. Both diseases commonly involve the colon.
Zain Majid, Shoaib Ahmed Khan, Hina Ismail, Nishat Akbar, Rajesh Mandhwani, Nasir Luck   +5 more
doaj   +1 more source

The Use and Role of Mesalamine in the Treatment of Ulcerative Colitis: A Literature Review [PDF]

Cureus
Shalvin Chand, Manvitha Bendagiri Matam, Nehal K Bhatt, Sanathanan Neelakantan Ramaswamy, Samyuktha Harikrishnan, Yashasvi Agarwal, Lubna Mohammed   +6 more
openalex   +2 more sources

Distal Ulcerative Colitis Refractory to Rectal Mesalamine: Role of Transdermal Nicotine versus Oral Mesalamine [PDF]

, 2002
BACKGROUND: Distal ulcerative colitis usually responds to treatment with rectal mesalamine, but the management of refractory cases is poorly ...
Mario Guslandi, Pier Alberto Testoni, Roberto Frego, Edi Viale   +3 more
core   +1 more source