Adjunctive Pentoxifylline Enhances Clinical Remission and Reduces Inflammatory Biomarkers in Mild-to-Moderate Ulcerative Colitis: A Randomized Double-Blind Placebo-Controlled Pilot Trial [PDF]
Background: Despite mesalamine’s efficacy in mild-to-moderate ulcerative colitis (UC), many patients fail to achieve complete clinical or biochemical remission.
Mohannad O. Khrieba +15 more
doaj +2 more sources
David Pierce,1 Mary Corcoran,2 Patrick Martin,2 Karen Barrett,1 Susi Inglis,1 Peter Preston,2 Thomas N Thompson,3 Sandra K Willsie3 1Shire, Basingstoke, UK; 2Shire, Wayne, PA, USA; 3PRA International, Lenexa, KS, USA Background: MMX® mesalamine is a
Pierce D +7 more
doaj +1 more source
Effect of mesalamine on healing in experimental colon anastomosis: A randomised experimental study
ObjectiveWe aimed to investigate the effect of mesalamine on healing of experimental colon anastomosis model.Material/MethodsForty adult male Wistar albino rats were performed segmentary colonic resection and end-to-end anastomosis. Animals were randomly
Ahmet Aslan +2 more
exaly +2 more sources
Background & Aims: Little is known about the effects of discontinuing mesalamine therapy for patients with Crohn's disease (CD) who initiate therapy with an anti–tumor necrosis factor (anti-TNF) agent.
Ryan C Ungaro +2 more
exaly +2 more sources
Mesalamine-Induced Eosinophilic Pneumonia [PDF]
Eosinophilic pneumonia encompasses a group of lung disorders characterized by peripheral blood eosinophilia. While its etiology is often idiopathic or infectious, non-infectious causes, including drug-induced reactions, should also be considered. Common culprits of drug-induced eosinophilic pneumonia include daptomycin, phenytoin, and nitrofurantoin ...
Sharma, Monish +2 more
openaire +3 more sources
Cap Polyposis Mimicking Rectal Neoplasia in an Adolescent [PDF]
United European Gastroenterology Journal, Volume 14, Issue 4, May 2026.
Meng Huang, Jie Wu
wiley +2 more sources
Systematic Review and Meta-analysis: Efficacy of Mesalamine in Irritable Bowel Syndrome [PDF]
Background & Aims Some patients with irritable bowel syndrome (IBS) demonstrate low-grade inflammation in the intestine. Mesalamine, which has anti-inflammatory effects, may be an efficacious treatment for IBS, but studies are conflicting.
Vivek C Goodoory +2 more
exaly +2 more sources
Patient considerations in the management of ulcerative colitis: role of once-daily MMX mesalamine
Daniel B Zandman, Mark A PeppercornHarvard Medical School, Division of Gastroenterology, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USAAbstract: Mesalamine and its derivatives are effective and well-tolerated therapies for ...
Daniel B Zandman, Mark A Peppercorn
doaj +1 more source
Drug-Induced Intersticial Nephritis. Clinical Case
5-Aminosalicylic acid (5-ASA) preparations are widely used in the treatment of inflammatory bowel diseases. The most commonly used medicine is mesalamine. Overall, it is a very safe drug with few side effects.
Paulina Tekoriutė +2 more
doaj +1 more source
Design and biological evaluation of mesalamine–NSAID hybrids targeting the NLRP3 inflammasome: a multi-target strategy for ulcerative colitis therapy [PDF]
Misagh Yahya +4 more
openalex +2 more sources

