An Orally Administered Redox Nanoparticle That Accumulates in the Colonic Mucosa and Reduces Colitis in Mice [PDF]
, 2012 Background & AimsDrugs used to treat patients with ulcerative colitis are not always effective because of nonspecific distribution, metabolism in the gastrointestinal tract, and side effects. We designed a nitroxide radical-containing nanoparticle (RNPO)
Matsui Hirofumi +6 more
core +1 more source
Suppository treatment in ulcerative proctitis
European Journal of Inflammation, 2021 Ulcerative proctitis (UP) is a common form of ulcerative colitis (UC), the number of patients with UP is increasing. Suppository treatment containing mesalamine is usually the first-line choice for mild to moderate UP, here, we review the publications on
Yingjie Si +3 more
doaj +1 more source
Successful management of HIV infection in a patient with ulcerative colitis; a case report [PDF]
Journal of Preventive Epidemiology, 2021 Human immunodeficiency virus (HIV) is an infectious disease that is rarely seen in ulcerative colitis patients. Both diseases commonly involve the colon.
Zain Majid +5 more
doaj +1 more source
Release of 5-Aminosalicylic Acid (5-ASA) from Mesalamine Formulations at Various pH Levels [PDF]
, 2015 INTRODUCTION: Oral formulations of 5-aminosalicylic acid (5-ASA) for treatment of ulcerative colitis have been developed to minimize absorption prior to the drug reaching the colon.
Adeyinka Abinusawa, Srini Tenjarla
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Myocarditis Secondary to Mesalamine-Induced Cardiotoxicity in a Patient with Ulcerative Colitis
Case Reports in Medicine, 2018 Development of cardiac manifestations in patients diagnosed with inflammatory bowel disease undergoing treatment with mesalamine is a rare. When this occurs, it can be difficult to tease out the primary etiology, as both IBD and mesalamine can cause ...
Kelechukwu U. Okoro +2 more
doaj +1 more source
Recent advances in understanding and managing diverticulitis. [PDF]
, 2018 In the past few decades, the increasing socioeconomic burden of acute diverticulitis (AD) has become evident, and with the growth of the population age, this significant economic impact will likely continue to rise. Furthermore, recent evidence showed an
Annibale, Bruno +4 more
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Probiotics in the treatment of diverticular disease. A systematic review [PDF]
, 2016 BACKGROUND AND AIMS: Diverticular disease is a common gastrointestinal condition. Low-grade inflammation and altered intestinal microbiota have been identified as factors contributing to abdominal symptoms.
ANNIBALE, Bruno +5 more
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ACS Omega, 2022 In the present study, a green and ecofriendly nanocatalyst was synthesized through functionalization of 2,4,6-trichloro-1,3,5-triazine (TCT) and mesalamine on silica-coated magnetic nanoparticles (MNPs), then coordination with Cu2+ without agglomeration,
Hooman Taherkhani +4 more
semanticscholar +1 more source
Mucosal Healing in Ulcerative Colitis: A Comprehensive Review [PDF]
, 2017 Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by periods of remission and periods of relapse. Patients often present with symptoms such as rectal bleeding, diarrhea and weight loss, and may require hospitalization and even
A Bitton +104 more
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Design and Characterization of Mesalamine Loaded Nanoparticles for Controlled Delivery System [PDF]
Nanomedicine Research Journal, 2016 Objective(s): Nanoparticles (NPs) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects.
Simin Seifirad +4 more
doaj +1 more source