Results 51 to 60 of about 6,343 (174)

Simple and sensitive spectrophotometric methods for the analysis of mesalamine in bulk and tablet dosage forms

Química Nova, 2011
Three simple, sensitive, economical and reproducible spectrophotometric methods (A, B and C) are described for determination of mesalamine in pure drug as well as in tablet dosage forms. Method A is based on the reduction of tungstate and/or molybdate in
Bala Sekaran Chandra, Siva Santhosh Bhogela, Manjusha Shaik, Chaitanya Sravanthi Vadlamudi, Meghana Chappa, Naga Sirisha Maddirala   +5 more
doaj   +1 more source

Outcomes and adverse effects of teduglutide treatment with periodic withdrawal in pediatric short bowel patients

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 1, Page 37-45, July 2026.
Abstract Objectives We evaluated the efficacy and safety of teduglutide in a real‐world cohort in which national reimbursement policies required treatment interruptions. The primary outcomes were reduction in parenteral support (PS) and treatment‐related adverse effects, and the secondary outcome was the impact of the mandated withdrawal periods ...
Riikka Gunnar, Annika Mutanen, Mikko P. Pakarinen, Laura Merras‐Salmio   +3 more
wiley   +1 more source

Effect of Intestinal Microbiota Transplantation on Intestinal Flora and Inflammatory Factor Levels in Patients with Ulcerative Colitis

Infection and Drug Resistance, 2023
Zhi Wang,1,* Li Yang,2,* Shan Sun2 1Pediatric Gastrointestinal Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, People’s Republic of China; 2Gastroenterology, Sinopharm Dongfeng General Hospital, Hubei ...
Wang Z, Yang L, Sun S
doaj  

Liver Injury From Medications Used for Treating Inflammatory Bowel Disease: The Drug‐Induced Liver Injury Network Experience

Liver International, Volume 46, Issue 7, July 2026.
ABSTRACT Background We aimed to investigate and characterise DILI due to approved therapies for inflammatory bowel disease (IBD). Methods Using the Drug‐Induced Liver Injury Network (DILIN) prospective study, we evaluated definite, highly likely, or probable DILI attributed to IBD therapies, including use for non‐IBD indications (but excluding ...
Harish Gopalakrishna, Jiezhun Gu, Yi‐Ju Li, Huiman Barnhart, Dina Halegoua‐DeMarzio, Herbert L. Bonkovsky, A. Sidney Barritt, Jean P. Molleston, Naga P. Chalasani, Marwan Ghabril   +9 more
wiley   +1 more source

Determination of Mesalamine Related Impurities from Drug Product by Reversed Phase Validated UPLC Method

E-Journal of Chemistry, 2011
In the present study gradient reversed-phase UPLC method was developed for simultaneous determination and separation of impurities and degradation products from drug product.
Trivedi Rakshit Kanubhai, Patel Mukesh C, Kharkar Amit R   +2 more
doaj   +1 more source

Water-in-Water Emulsion as a New Approach to Produce Mesalamine-Loaded Xylan-Based Microparticles

Applied Sciences, 2019
The water-in-water emulsion method has been reported as a technique able to prepare microparticles without using harmful solvents. However, there are few reports showing the encapsulation of small molecules into microparticles produced within this ...
Bartolomeu S. Souza, Henrique R. Marcelino, Francisco Alexandrino, Silvana C. C. Urtiga, Karen C. H. Silva, Daniel C. F. Soares, Eryvaldo S. T. Egito   +6 more
doaj   +1 more source

Randomized Controlled Trial on the Effectiveness of a Telehealth Gamification App for Self‐Management in Patients With Inflammatory Bowel Disease

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Inflammatory bowel diseases (IBDs) are chronic, relapsing‐remitting disorders that significantly impair quality of life and increase healthcare utilization. Although effective therapies are available, suboptimal adherence and insufficient monitoring often compromise disease control.
Narges Norouzkhani, Mahbobeh Faramarzi, Ali Bahari, Javad Shokri Shirvani, Hamed Tabesh   +4 more
wiley   +1 more source

Metformin as a Multifaceted Therapeutic Agent for Gastrointestinal Diseases: Mechanisms, Clinical Efficacy, and Future Directions

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT The high prevalence of gastrointestinal (GI) diseases and their significant impact on the quality of life require new therapeutic strategies. The development of novel therapeutic strategies should prioritize targeting the fundamental pathophysiological mechanisms underlying these diseases, including inflammation, cellular proliferation, and ...
Sayedeh Azimeh Hosseini, Hassan Valadbeigi, Seyedeh Mahdieh Khoshnazar, Saeed Khoshnood, Shahab Falahi, Delsuz Rezaee, Ali Hematian, Mohammad Hossein Haddadi   +7 more
wiley   +1 more source

Practices and perceptions of 5-aminosalicylic acid use in Crohn’s disease: a nationwide survey of physicians in Korea by KASID Guidelines Taskforce Team [PDF]

Intestinal Research
Background/Aims Despite international guidelines recommending against the use of 5-aminosalicylic acid (5-ASA) for Crohn’s disease (CD), it remains widely prescribed.
June Hwa Bae, Seung Yong Shin, Dong Hyun Kim, Seung Min Hong, Eun Mi Song, Ji Eun Kim, Young Joo Yang, Jiyoung Yoon, Sang-Bum Kang, Eun Soo Kim, Sung Eun Kim, Seong-Jung Kim, Jun Lee, Soo-Young Na, Soo Jung Park, Sang Hyoung Park, Won Moon, Sung-Ae Jung,   +18 more
doaj   +1 more source

The Polyphosphate Kinase of Escherichia coli Is Required for Full Production of the Genotoxin Colibactin

mSphere, 2020
Colibactin induces DNA damage in mammalian cells and has been linked to the virulence of Escherichia coli and the promotion of colorectal cancer (CRC). By looking for mutants attenuated in the promoter activity of clbB encoding one of the key enzymes for
Min Tang-Fichaux, Camille V. Chagneau, Nadège Bossuet-Greif, Jean-Philippe Nougayrède, Éric Oswald, Priscilla Branchu   +5 more
doaj   +1 more source