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Inflammatory Bowel Disease [PDF]

New England Journal of Medicine, 2009
Inflammatory bowel diseases (IBDs) encompass ulcerative colitis, Crohn's disease, and indeterminate colitis, all of which are characterized by remission and exacerbation of gastrointestinal symptoms, and a variety of extraintestinal manifestations including those affecting the oral cavity.
Clara Abraham, Judy Cho, Cho Judy H
exaly   +8 more sources

Novel Utility of Leucine-Rich Alpha-2-Glycoprotein as a Biomarker in Ulcerative Colitis: A Predictor of Endoscopic Remission Independent of Symptoms

Inflammatory Intestinal Diseases, 2023
Introduction: Leucine-rich alpha-2-glycoprotein (LRG) is a potential biomarker for disease activity and reflects mucosal healing in patients with ulcerative colitis (UC).
Tomoyuki Hayashi, Kazuya Kitamura, Masaaki Usami, Masaki Miyazawa, Masaki Nishitani, Akihiro Dejima, Makoto Yamamoto, Shotaro Kawase, Masaya Funaki, Noriaki Orita, Hidetoshi Nakagawa, Koki Morita, Noriho Iida, Akihiro Seki, Kouki Nio, Hidenori Kido, Hideo Takayama, Yuta Takeuchi, Shinya Yamada, Hajime Takatori, Mari Shimada, Hiroto Saito, Daisuke Yamamoto, Tadashi Toyama, Taro Yamashita   +24 more
doaj   +1 more source

Inflammatory bowel disease [PDF]

BMJ, 2015
Scandinavian researchers have contributed to the present understanding of inflammatory bowel disease (IBD). Important epidemiological data and family risk factors have been reported from all the Nordic countries, original twin studies mainly from Denmark and Sweden, and relationships to cancer and surgery mostly from Sweden.
Ella, Mozdiak, John, O'Malley, Ramesh, Arasaradnam   +2 more
openaire   +5 more sources

Inflammatory Bowel Disease [PDF]

Evolution, Medicine, and Public Health, 2014
Inflammatory bowel diseases (IBD), including Crohn's disease (CD) and ulcerative colitis (UC), are chronic, relapsing inflammatory condition of the gastrointestinal tract. CD and UC have distinct pathologic and clinical characteristics and despite the extensive amount of research conducted over the past decades, their pathogenesis remains still poorly ...
Lee, Shona J., Maizels, Rick M.
openaire   +5 more sources

Endoplasmic Reticulum Stress in Colonic Mucosa of Ulcerative Colitis Patients Is Mediated by PERK and IRE1 Pathway Activation

Mediators of Inflammation, 2022
Ulcerative colitis (UC) is characterized by a chronic overproduction of proinflammatory cytokines. During an acute phase, the endoplasmic reticulum (ER) is overloaded and the protein folding process is impaired, a condition named ER stress.
Bruno Lima Rodrigues, Isabella Dotti, Lívia Bitencourt Pascoal, Joseane Morari, Miriam Esteller, Andressa Coope, Maria de Lourdes Setsuko Ayrizono, Azucena Salas, Raquel Franco Leal   +8 more
doaj   +1 more source

Inflammatory bowel disease [PDF]

Archives of Disease in Childhood, 2006
Twenty five per cent of inflammatory bowel disease presents in childhood. Growth and nutrition are key issues in the management with the aim of treatment being to induce and then maintain disease remission with minimal side effects. Only 25% of Crohn's disease presents with the classic triad of abdominal pain, weight loss, and diarrhoea.
R M, Beattie, N M, Croft, J M, Fell, N A, Afzal, R B, Heuschkel   +4 more
openaire   +2 more sources

Impact of the body mass index on the retention of the anorectal mucosa after double-stapled ileal pouch-anal anastomosis for ulcerative colitis

BMC Gastroenterology, 2023
Background Double-stapled ileal pouch-anal anastomosis (DS-IPAA) is easy to construct and has a good functional outcome in patients with ulcerative colitis (UC). However, retention of the anorectal mucosa may lead to a subsequent risk of inflammation and
Hideaki Kimura, Kenichiro Toritani, Reiko Kunisaki, Kenji Tatsumi, Kazutaka Koganei, Akira Sugita, Itaru Endo   +6 more
doaj   +1 more source

Inflammatory bowel disease [PDF]

Primary Care: Clinics in Office Practice, 2001
Idiopathic inflammatory bowel disease consists of Crohn's disease and ulcerative colitis. Crohn's disease can affect any part of the gastrointestinal tract, from the mouth to the anus, and is also known as regional enteritis, terminal ileitis, or granulomatous colitis.
D J, Helper, D K, Rex
  +7 more sources

Clinicopathological and prognostic evaluations of anorectal cancer after fecal diversion for patients with Crohn’s disease

BMC Gastroenterology, 2021
Purpose Colorectum diversion with a proximal stoma is often the preferred surgical approach in patients with Crohn's disease-related anorectal lesions or refractory colitis.
Hirosuke Kuroki, Akira Sugita, Kazutaka Koganei, Kenji Tatsumi, Ryo Futatsuki, Eiichi Nakao, Nao Obara, Katsuhiko Arai   +7 more
doaj   +1 more source

Clinical features and surgical selection in colitis-associated colorectal cancer with ulcerative colitis

BMC Surgery, 2023
Purpose The aim of this study was to compare the clinical characteristics of ulcerative colitis (UC) patients who underwent surgery for cancer/dysplasia with those who underwent surgery for refractory disease and to discuss the preoperative preparation ...
Ryuichi Kuwahara, Hiroki Ikeuchi, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Kei Kimura, Kozo Kataoka, Naohito Beppu, Masataka Ikeda, Motoi Uchino   +9 more
doaj   +1 more source