Results 21 to 30 of about 7,176,980 (297)

Vedolizumab for perianal fistulizing Crohn’s disease: systematic review and meta-analysis [PDF]

Intestinal Research, 2022
Background/Aims Perianal fistulas are a debilitating manifestation of Crohn’s disease (CD). Despite the advent of anti-tumor necrosis factor (anti-TNF) therapy, the medical management of fistulizing CD continues to be challenged by unmet needs.
Fares Ayoub, Matthew Odenwald, Dejan Micic, Sushila R. Dalal, Joel Pekow, Russell D. Cohen, David T. Rubin, Atsushi Sakuraba   +7 more
doaj   +1 more source

The Influence of Probiotics on the Firmicutes/Bacteroidetes Ratio in the Treatment of Obesity and Inflammatory Bowel disease

Microorganisms, 2020
The two most important bacterial phyla in the gastrointestinal tract, Firmicutes and Bacteroidetes, have gained much attention in recent years. The Firmicutes/Bacteroidetes (F/B) ratio is widely accepted to have an important influence in maintaining ...
S. Stojanov, A. Berlec, B. S̆trukelj
semanticscholar   +1 more source

Treatment of Inflammatory Bowel Disease: A Comprehensive Review

Frontiers in Medicine, 2021
Inflammatory bowel disease (IBD), as a global disease, has attracted much research interest. Constant research has led to a better understanding of the disease condition and further promoted its management. We here reviewed the conventional and the novel
Zhao-Bei Cai, Shu Wang, Jian-Nan Li
semanticscholar   +1 more source

Change in hematologic indices over time in pediatric inflammatory bowel disease treated with azathioprine [PDF]

, 2010
Azathioprine leads to changes in mean corpuscular volume (MCV) and white blood cell (WBC) indices reflecting efficacy or toxicity. Understanding the interactions between bone marrow stem cells and azathioprine could highlight abnormal response patterns ...
Cordell, Samantha J., Sally A. Connolly, Dhandapani Ashok, Chris J. Taylor, Ashok, Dhandapani, Taylor, Chris J., Connolly, Sally A., Soman, Sherman, Samantha J. Cordell, Sherman Soman, Campbell, David I., David I. Campbell   +11 more
core   +1 more source

Association between serum tumor necrosis factor-alpha level and the efficacy of infliximab for refractory pouchitis after restorative proctocolectomy in patients with ulcerative colitis

Journal of the Anus, Rectum and Colon, 2017
Objectives: Although the aetiology of pouchitis after restorative proctocolectomy in ulcerative colitis (UC) remains unknown, infliximab (IFX) is often effective for this condition. However, indicators and predictors of treatment efficacy remain unclear.
Motoi Uchino, Hiroki Ikeuchi, Toshihiro Bando, Akihiro Hirata, Teruhiro Chohno, Hirofumi Sasaki, Yuki Horio, Shiro Nakamura   +7 more
doaj   +1 more source

Inflammatory bowel disease-specific autoantibodies in HLA-B27-associated spondyloarthropathies: Increased prevalence of ASCA and pANCA [PDF]

, 2004
Aims: An association between inflammatory bowel disease (IBD) and spondyloarthropathies (SpA) has repeatedly been reported. The aim of the present study was to investigate whether serologic markers of IBD, e. g.
Folwaczny, Christian, Kellner, H., J. Glas, Marker-Hermann, E., R. Gruber, Brumberger, V., V. Brumberger, Glas, J., Gruber, R., H. Kellner, C. Folwaczny, Török, H.-P., E. Märker-Hermann, C. Strasser, Strasser, C., H.-P. Török   +15 more
core   +1 more source

Cap polyposis treated with laparoscopic-assisted total proctocolectomy and ileal J-pouch anal anastomosis: a case report

Surgical Case Reports, 2021
Background Cap polyposis (CP) is extremely rare in Japan, and there is no established cure. We report a case in which CP was improved by surgical treatment.
Tomohiro Minagawa, Hiroki Ikeuchi, Kurando Kusunoki, Ryuichi Kuwahara, Yuki Horio, Takako Kihara, Seiichi Hirota, Motoi Uchino   +7 more
doaj   +1 more source

Rectal-sparing type of ulcerative colitis predicts lack of response to pharmacotherapies

BMC Surgery, 2017
Background Ulcerative colitis (UC) is known as an immune disorder of the colon that generally involves the rectum, but an atypical distribution of inflamed mucosa has previously been noted in certain subtypes of UC, such as the rectal-sparing type (RST).
Yuki Horio, Motoi Uchino, Toshihiro Bando, Teruhiro Chohno, Hirofumi Sasaki, Akihiro Hirata, Yoshio Takesue, Hiroki Ikeuchi   +7 more
doaj   +1 more source

The four epidemiological stages in the global evolution of inflammatory bowel disease

Nature reviews: Gastroenterology & hepatology, 2020
Inflammatory bowel disease (IBD) is a global disease; its evolution can be stratified into four epidemiological stages: Emergence, Acceleration in Incidence, Compounding Prevalence and Prevalence Equilibrium.
G. Kaplan, J. Windsor
semanticscholar   +1 more source

Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease [PDF]

, 2008
AIM:To investigate the efficacy of 6-mercaptopurine (6-MP) in cases of azathioprine (AZA) hypersensitivity in patients with inflammatory bowel disease. METHODS: Twenty nine previously confirmed Crohn’s disease (CD) (n = 14) and ulcerative colitis (UC)
Nagy, Ferenc, Lonovics, János, Farkas, Kaludia, Molnár, Tamás, Szepes, Zoltán, Nyári, Tibor András   +5 more
core   +1 more source