Results 21 to 30 of about 5,849,239 (280)

Inflammatory Bowel Disease [PDF]

Annual Review of Immunology, 2010
Insights into inflammatory bowel disease (IBD) are advancing rapidly owing to immunologic investigations of a plethora of animal models of intestinal inflammation, ground-breaking advances in the interrogation of diseases that are inherited as complex genetic traits, and the development of culture-independent methods to define the composition of the ...
Arthur, Kaser, Sebastian, Zeissig, Richard S, Blumberg   +2 more
openaire   +5 more sources

Clinical features and surgical selection in colitis-associated colorectal cancer with ulcerative colitis

BMC Surgery, 2023
Purpose The aim of this study was to compare the clinical characteristics of ulcerative colitis (UC) patients who underwent surgery for cancer/dysplasia with those who underwent surgery for refractory disease and to discuss the preoperative preparation ...
Ryuichi Kuwahara, Hiroki Ikeuchi, Kurando Kusunoki, Tomohiro Minagawa, Yuki Horio, Kei Kimura, Kozo Kataoka, Naohito Beppu, Masataka Ikeda, Motoi Uchino   +9 more
doaj   +1 more source

Candidate genes colocalized to linkage regions in inflammatory bowel disease [PDF]

, 2002
Background and Aims: The genes encoding for tumor necrosis factor-alpha (TNF-alpha), epidermal growth factor receptor (EGFR) and the vitamin D receptor (VDR) are colocalized to inflammatory bowel disease-associated linkage regions on chromosomes 6, 7 and
Folwaczny, Christian, Radimayr, M., Heinzlmann, M., Borchers, R., Martin, K.   +4 more
core   +1 more source

Smoking in inflammatory bowel diseases: Good, bad or ugly? [PDF]

, 2007
Smoking is an important environmental factor in inflammatory bowel disease (IBD), having different effects in ulcerative colitis (UC) and Crohn’s disease (CD).
Peter Laszlo Lakatos, Lakatos, Péter László, Tamas Szamosi, Szamosi, Tamás, Laszlo Lakatos, Lakatos, László   +5 more
core   +1 more source

Clinical Results of One-stage Restorative Proctocolectomy with J-pouch Anal Anastomosis in 300 Ulcerative Colitis Patients

Journal of the Anus, Rectum and Colon, 2020
Objectives: Restorative proctocolectomy and ileal pouch anal anastomosis (IPAA), with diverting ileostomy, are established ulcerative colitis (UC) treatments.
Ryuichi Kuwahara, Hiroki Ikeuchi, Toshihiro Bando, Hirohumi Sasaki, Yoshiko Goto, Yuki Horio, Tomohiro Minagawa, Motoi Uchino   +7 more
doaj   +1 more source

A decade of inflammatory bowel disease: a single center experience in Egypt

The Egyptian Journal of Internal Medicine, 2022
Background Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract and includes ulcerative colitis and Crohn’s disease. Inflammatory bowel disease has always seemed to be rare in the Middle East and Northern Africa. In
Mostafa Abd Alfattah Shamkh, Mohamed Amin Sakr, Waleed Hamed Abd Alaty, Shimaa Youssef Kamel, Mohamed Mahmoud Eltabbakh, Ahmed Fouad Sherief, Heba Rashad, Safaa Askar   +7 more
doaj   +1 more source

Vedolizumab for perianal fistulizing Crohn’s disease: systematic review and meta-analysis [PDF]

Intestinal Research, 2022
Background/Aims Perianal fistulas are a debilitating manifestation of Crohn’s disease (CD). Despite the advent of anti-tumor necrosis factor (anti-TNF) therapy, the medical management of fistulizing CD continues to be challenged by unmet needs.
Fares Ayoub, Matthew Odenwald, Dejan Micic, Sushila R. Dalal, Joel Pekow, Russell D. Cohen, David T. Rubin, Atsushi Sakuraba   +7 more
doaj   +1 more source

Analysis of IL12B gene variants in inflammatory bowel disease [PDF]

, 2012
IL12B encodes the p40 subunit of IL-12, which is also part of IL-23. Recent genome-wide association studies identified IL12B and IL23R as susceptibility genes for inflammatory bowel disease (IBD).
Darina Czamara, Seiderer, J., Seiderer Julia, Ochsenkühn, Thomas, Fries, C., Julia Seiderer (107820), Beigel, F., Wagner, Johanna, Glas, J., Cornelia Tillack (174718), Friedrich, Matthias, Christian Steib (174731), Czamara, D., Diegelmann Julia, Jürgen Glas (107816), Fries Christoph, Tillack, Cornelia, Friedrich Matthias, Steib Christian, Stallhofer, Johannes, Torsten Olszak (107835), Brand, Stephan, Göke, B., Florian Beigel (174724), Brand Stephan, Thomas Ochsenkühn, Olszak Torsten, Beigel, Florian, Matthias Friedrich (174721), Thomas Ochsenkühn (174734), Stallhofer, J., Ochsenkühn, T., Johannes Stallhofer, Matthias Friedrich, Wetzke, M., Darina Czamara (107824), Stephan Brand (107861), Cornelia Tillack, Julia Diegelmann, Beigel Florian, Steib, Christian, Göke, Burkhard, Wetzke Martin, Fries, Christoph, Wagner, J., Friedrich, M., Seiderer, Julia, Glas, Jürgen, Diegelmann, J., Burkhard Göke (109829), Christoph Fries, Ochsenkühn Thomas, Wagner Johanna, Martin Wetzke, Burkhard Göke, Göke Burkhard, Christian Steib, Stephan Brand, Brand, S., Steib, C., Czamara, Darina, Martin Wetzke (107833), Stallhofer Johannes, Julia Diegelmann (107830), Jürgen Glas, Johanna Wagner (174709), Tillack Cornelia, Johanna Wagner, Wetzke, Martin, Czamara Darina, Diegelmann, Julia, Christoph Fries (174714), Johannes Stallhofer (174728), Glas Jürgen, Torsten Olszak, Olszak, T., Florian Beigel, Julia Seiderer, Olszak, Torsten, Tillack, C.   +79 more
core   +2 more sources

Association between serum tumor necrosis factor-alpha level and the efficacy of infliximab for refractory pouchitis after restorative proctocolectomy in patients with ulcerative colitis

Journal of the Anus, Rectum and Colon, 2017
Objectives: Although the aetiology of pouchitis after restorative proctocolectomy in ulcerative colitis (UC) remains unknown, infliximab (IFX) is often effective for this condition. However, indicators and predictors of treatment efficacy remain unclear.
Motoi Uchino, Hiroki Ikeuchi, Toshihiro Bando, Akihiro Hirata, Teruhiro Chohno, Hirofumi Sasaki, Yuki Horio, Shiro Nakamura   +7 more
doaj   +1 more source

Cap polyposis treated with laparoscopic-assisted total proctocolectomy and ileal J-pouch anal anastomosis: a case report

Surgical Case Reports, 2021
Background Cap polyposis (CP) is extremely rare in Japan, and there is no established cure. We report a case in which CP was improved by surgical treatment.
Tomohiro Minagawa, Hiroki Ikeuchi, Kurando Kusunoki, Ryuichi Kuwahara, Yuki Horio, Takako Kihara, Seiichi Hirota, Motoi Uchino   +7 more
doaj   +1 more source