Results 11 to 20 of about 316,954 (250)

Clinical Results of One-stage Restorative Proctocolectomy with J-pouch Anal Anastomosis in 300 Ulcerative Colitis Patients

Journal of the Anus, Rectum and Colon, 2020
Objectives: Restorative proctocolectomy and ileal pouch anal anastomosis (IPAA), with diverting ileostomy, are established ulcerative colitis (UC) treatments.
Ryuichi Kuwahara, Hiroki Ikeuchi, Toshihiro Bando, Hirohumi Sasaki, Yoshiko Goto, Yuki Horio, Tomohiro Minagawa, Motoi Uchino   +7 more
doaj   +1 more source

A decade of inflammatory bowel disease: a single center experience in Egypt

The Egyptian Journal of Internal Medicine, 2022
Background Inflammatory bowel disease is a chronic inflammatory disorder of the gastrointestinal tract and includes ulcerative colitis and Crohn’s disease. Inflammatory bowel disease has always seemed to be rare in the Middle East and Northern Africa. In
Mostafa Abd Alfattah Shamkh, Mohamed Amin Sakr, Waleed Hamed Abd Alaty, Shimaa Youssef Kamel, Mohamed Mahmoud Eltabbakh, Ahmed Fouad Sherief, Heba Rashad, Safaa Askar   +7 more
doaj   +1 more source

Vedolizumab for perianal fistulizing Crohn’s disease: systematic review and meta-analysis [PDF]

Intestinal Research, 2022
Background/Aims Perianal fistulas are a debilitating manifestation of Crohn’s disease (CD). Despite the advent of anti-tumor necrosis factor (anti-TNF) therapy, the medical management of fistulizing CD continues to be challenged by unmet needs.
Fares Ayoub, Matthew Odenwald, Dejan Micic, Sushila R. Dalal, Joel Pekow, Russell D. Cohen, David T. Rubin, Atsushi Sakuraba   +7 more
doaj   +1 more source

Association between serum tumor necrosis factor-alpha level and the efficacy of infliximab for refractory pouchitis after restorative proctocolectomy in patients with ulcerative colitis

Journal of the Anus, Rectum and Colon, 2017
Objectives: Although the aetiology of pouchitis after restorative proctocolectomy in ulcerative colitis (UC) remains unknown, infliximab (IFX) is often effective for this condition. However, indicators and predictors of treatment efficacy remain unclear.
Motoi Uchino, Hiroki Ikeuchi, Toshihiro Bando, Akihiro Hirata, Teruhiro Chohno, Hirofumi Sasaki, Yuki Horio, Shiro Nakamura   +7 more
doaj   +1 more source

Cap polyposis treated with laparoscopic-assisted total proctocolectomy and ileal J-pouch anal anastomosis: a case report

Surgical Case Reports, 2021
Background Cap polyposis (CP) is extremely rare in Japan, and there is no established cure. We report a case in which CP was improved by surgical treatment.
Tomohiro Minagawa, Hiroki Ikeuchi, Kurando Kusunoki, Ryuichi Kuwahara, Yuki Horio, Takako Kihara, Seiichi Hirota, Motoi Uchino   +7 more
doaj   +1 more source

Faecal calprotectin level for assessing endoscopic activity and predicting future clinical course in patients with moderately active ulcerative colitis undergoing granulomonocytapheresis: a prospective cohort study

BMC Gastroenterology, 2018
Background Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC).
Takahiro Shimoyama, Takayuki Yamamoto, Satoru Umegae, Koichi Matsumoto   +3 more
doaj   +1 more source

Factors associated with poor compliance amongst hospitalized, predominantly adolescent pediatric Crohn’s disease patients

Annals of Medicine, 2022
Background Compliance with medical treatment is vital for the control of inflammatory bowel disease (IBD) and prevention of disease complications and is an issue in paediatric patients.
Nathaniel A. Cohen, Dejan M. Micic, Atsushi Sakuraba   +2 more
doaj   +1 more source

Rectal-sparing type of ulcerative colitis predicts lack of response to pharmacotherapies

BMC Surgery, 2017
Background Ulcerative colitis (UC) is known as an immune disorder of the colon that generally involves the rectum, but an atypical distribution of inflamed mucosa has previously been noted in certain subtypes of UC, such as the rectal-sparing type (RST).
Yuki Horio, Motoi Uchino, Toshihiro Bando, Teruhiro Chohno, Hirofumi Sasaki, Akihiro Hirata, Yoshio Takesue, Hiroki Ikeuchi   +7 more
doaj   +1 more source

The Use of Oral Herbal Medicine (Hange-Shashin-To) in Patients with Pouchitis: A Pilot Study

Journal of the Anus, Rectum and Colon, 2018
Objectives: Hange-Shashin-To (HST), which is a combination of seven herbs, has previously been used in the treatment of inflammatory or ulcerative gut disease.
Hiroki Matsuoka, Motoi Uchino, Yuki Horio, Hirofumi Sasaki, Teruhiro Chohno, Akihiro Hirata, Toshihiro Bando, Takashi Ito, Toshimasa Yamaguchi, Hiroki Ikeuchi   +9 more
doaj   +1 more source

Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan [PDF]

Intestinal Research, 2019
Background/Aims Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance therapy in Japanese children with ...
Tadahiro Yanagi, Kosuke Ushijima, Hidenobu Koga, Takeshi Tomomasa, Hitoshi Tajiri, Reiko Kunisaki, Takashi Isihige, Hiroyuki Yamada, Katsuhiro Arai, Atsushi Yoden, Tomoki Aomatsu, Satoru Nagata, Keiichi Uchida, Yoshikazu Ohtsuka, Toshiaki Shimizu   +14 more
doaj   +1 more source