Results 31 to 40 of about 5,849,239 (280)

Change in hematologic indices over time in pediatric inflammatory bowel disease treated with azathioprine [PDF]

open access: yes, 2010
Azathioprine leads to changes in mean corpuscular volume (MCV) and white blood cell (WBC) indices reflecting efficacy or toxicity. Understanding the interactions between bone marrow stem cells and azathioprine could highlight abnormal response patterns ...
Cordell, Samantha J.   +11 more
core   +1 more source

Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease [PDF]

open access: yes, 2010
PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core   +4 more sources

Rectal-sparing type of ulcerative colitis predicts lack of response to pharmacotherapies

open access: yesBMC Surgery, 2017
Background Ulcerative colitis (UC) is known as an immune disorder of the colon that generally involves the rectum, but an atypical distribution of inflamed mucosa has previously been noted in certain subtypes of UC, such as the rectal-sparing type (RST).
Yuki Horio   +7 more
doaj   +1 more source

Factors associated with poor compliance amongst hospitalized, predominantly adolescent pediatric Crohn’s disease patients

open access: yesAnnals of Medicine, 2022
Background Compliance with medical treatment is vital for the control of inflammatory bowel disease (IBD) and prevention of disease complications and is an issue in paediatric patients.
Nathaniel A. Cohen   +2 more
doaj   +1 more source

Clinical presentation of Crohn's disease. Association between familial disease, smoking, disease phenotype, extraintestinal manifestations and need for surgery [PDF]

open access: yes, 2005
Background/Aims: Recent molecular data suggest that genetic factors may underlie the disease heterogeneity observed in Crohn's disease (CD). It was also suggested that familial inflammatory bowel disease (IBD) is a homogenous subgroup, phenotypically ...
Gasztonyi, Beáta   +16 more
core   +3 more sources

Faecal calprotectin level for assessing endoscopic activity and predicting future clinical course in patients with moderately active ulcerative colitis undergoing granulomonocytapheresis: a prospective cohort study

open access: yesBMC Gastroenterology, 2018
Background Calprotectin is a stable neutrophil protein, which can be measured in faecal samples. The faecal level of calprotectin increases during disease activity in ulcerative colitis (UC).
Takahiro Shimoyama   +3 more
doaj   +1 more source

Mood and nonmood components of perceived stress and exacerbation of Crohnʼs disease [PDF]

open access: yes, 2011
BACKGROUND: Diverse psychological factors are involved in the pathophysiology of stress. In order to devise effective intervention strategies, it is important to elucidate which factors play the most important role in the association between ...
Begré, Stefan   +7 more
core   +1 more source

Efficacy of 6-mercaptopurine treatment after azathioprine hypersensitivity in inflammatory bowel disease [PDF]

open access: yes, 2008
AIM:To investigate the efficacy of 6-mercaptopurine (6-MP) in cases of azathioprine (AZA) hypersensitivity in patients with inflammatory bowel disease. METHODS: Twenty nine previously confirmed Crohn’s disease (CD) (n = 14) and ulcerative colitis (UC)
Nagy, Ferenc   +5 more
core   +1 more source

The Use of Oral Herbal Medicine (Hange-Shashin-To) in Patients with Pouchitis: A Pilot Study

open access: yesJournal of the Anus, Rectum and Colon, 2018
Objectives: Hange-Shashin-To (HST), which is a combination of seven herbs, has previously been used in the treatment of inflammatory or ulcerative gut disease.
Hiroki Matsuoka   +9 more
doaj   +1 more source

Tacrolimus for ulcerative colitis in children: a multicenter survey in Japan [PDF]

open access: yesIntestinal Research, 2019
Background/Aims Tacrolimus is effective for refractory ulcerative colitis in adults, while data for children is sparse. We aimed to evaluate the effectiveness and safety of tacrolimus for induction and maintenance therapy in Japanese children with ...
Tadahiro Yanagi   +14 more
doaj   +1 more source

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