A prospective evaluation of the predictive value of faecal calprotectin in quiescent Crohn’s disease [PDF]
Background: The faecal calprotectin (FC) test is a non-invasive marker for gastrointestinal inflammation. Aim: To determine whether higher FC levels in individuals with quiescent Crohn’s disease are associated with clinical relapse over the ensuing 12 ...
Allan J. Morris +50 more
core +1 more source
Background Colorectal carcinoma with enteroblastic differentiation is a rare subtype of colorectal carcinomas expressing at least one characteristic immunohistochemical marker among α-fetoprotein, glypican-3, and spalt-like transcription factor 4. On the
Takako Kihara +7 more
doaj +1 more source
Fibrotic and Vascular Remodelling of Colonic Wall in Patients with Active Ulcerative Colitis [PDF]
open16noIntestinal fibrosis is a complication of inflammatory bowel disease [IBD]. Although fibrostenosis is a rare event in ulcerative colitis [UC], there is evidence that a fibrotic rearrangement of the colon occurs in the later stages.
Bassotti, Gabrio +15 more
core +2 more sources
Living with Inflammatory Bowel Disease: A Crohn’s and Colitis Canada Survey
BACKGROUND: Despite improvements in therapies for inflammatory bowel diseases (IBDs), patient quality of life continues to be significantly impacted.
Helen M Becker +9 more
doaj +1 more source
DNA methylation-associated colonic mucosal immune and defense responses in treatment-naïve pediatric ulcerative colitis [PDF]
Inflammatory bowel diseases (IBD) are emerging globally, indicating that environmental factors may be important in their pathogenesis. Colonic mucosal epigenetic changes, such as DNA methylation, can occur in response to the environment and have been ...
Bronsky, Jiri +10 more
core +2 more sources
Current concept on the pathogenesis of inflammatory bowel disease-crosstalk between genetic and microbial factors: Pathogenic bacteria and altered bacterial sensing or changes in mucosal integrity take "toll"? [PDF]
The pathogenesis of inflammatory bowel disease (IBD) is only partially understood. Various environmental and host (e.g. genetic-, epithelial-, immune and non-immune) factors are involved.
Fischer, Simon +4 more
core +1 more source
Background/Aims: Recent genome-wide analyses have provided strong evidence concerning adverse events caused by thiopurine drugs such as azathioprine (AZA) and 6-mercaptopurine.
Toshiyuki Sato +13 more
doaj +1 more source
Faecal leukocyte esterase activity is an alternative biomarker in inflammatory bowel disease [PDF]
Background: Leukocyte cytosolic proteins (e.g., calprotectin) are emerging biomarkers for inflammatory bowel disease. Leukocyte aryl esterase activity has been commonly used for sensitive detection of leukocytes in human body fluids such as urine.
De Vos, Martine +5 more
core +2 more sources
Detecting and managing small bowel Crohn’s disease – capsule endoscopy becoming a first line diagnostic method? [PDF]
Small bowel endoscopy is crucial for diagnosing small bowel Crohn’s disease, and capsule endoscopy is complemented by balloon-assisted enteroscopy to take biopsies and by magnetic resonance imaging to visualize enteral and extra-intestinal involvement ...
Albert, Jörg Gerhard +1 more
core +1 more source
Objectives To evaluate the safety and utility of hybrid endoscopy for whole‐bowel assessment in Crohn's disease (CD) and its role in treatment decision‐making.
Takahiro Ito +4 more
doaj +1 more source

