Probiotics in arthralgia and spondyloarthropathies in patients with inflammatory bowel disease. Prospective randomized trials are necessary [PDF]
Arthralgias and spondyloarthropathies of the peripheral and axial joints are common in inflammatory bowel disease. Evidence for a strong association between these clinical manifestations and diseases of the joints has been provided by several clinical ...
Karimi, O., Pena, A.S.
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Nrf2 deficiency influences susceptibility to steroid resistance via HDAC2 reduction [PDF]
Abnormal lung inflammation and oxidant burden are associated with a significant reduction in histone deacetylase 2 (HDAC2) abundance and steroid resistance.
Adenuga +33 more
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Crohn's disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn's disease [PDF]
Traditionally, Crohn's disease has been associated with a Th1 cytokine profile, while Th2 cytokines are modulators of ulcerative colitis. This concept has been challenged by the description of tolerising regulatory T cells (Treg) and by proinflammatory ...
Brand, Stephan
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The evolving understanding of histology as an endpoint in ulcerative colitis [PDF]
A therapeutic goal for patients with ulcerative colitis (UC) is deep remission including clinical remission and mucosal healing. Mucosal healing was previously defined by endoscopic appearance, but recent studies demonstrate that histological ...
Shintaro Akiyama +2 more
doaj +1 more source
Aim In patients with failing ileo‐anal pouches there is often diagnostic uncertainty. In this setting, we may offer revisional pouch surgery with biologic “coverage” for presumed Crohn's disease (CD) which enables an alternative to pouch excision and end
Mehmet Gulmez +8 more
doaj +1 more source
Objectives: Minimally invasive surgery (MIS) is widely used for Crohn's disease (CD), but its feasibility in complex CD is still debated. This study aimed to evaluate short-term outcomes and identify factors associated with major complications following ...
Eiichi Nakao +6 more
doaj
Scintigraphy with 99mTc(V)-DMSA in monitoring patients with inflammatory bowel disease [PDF]
The clinical significance of pentavalent technetium-99m dimercaptosuccinic acid (99mTc(V)-DMSA) scintigraphy in diagnosing inflammatory bowel disease (IBD) has not yet been fully elucidated. The aim of this prospective paper was to study the above.
Abedi, J. +7 more
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Factors associated with long-term clinical outcome in microscopic colitis
Background and aims Microscopic colitis has been increasingly recognized as a cause of chronic diarrhoea. We aimed to characterize the role of disease-related factors and treatments on the clinical outcomes of microscopic colitis.Methods We ...
Yusuke Miyatani +5 more
doaj +1 more source
Mechanisms underlying bone loss associated with gut inflammation [PDF]
Patients with gastrointestinal diseases frequently suffer from skeletal abnormality, characterized by reduced bone mineral density, increased fracture risk, and/or joint inflammation.
Abu-Amer, Yousef, Arra, Manoj, Ke, Ke
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A Case Report of Multiple Aseptic Facial and Spinal Abscesses in a 45-Year-Old with Inflammatory Bowel Disease [PDF]
INTRODUCTION Sterile abscess syndrome is a rarely described entity that is often associated with auto-inflammatory disorders. Although clinically similar to septic abscesses, sterile abscesses are known to be unaffected by antibiotic regimens and ...
Francis, MD, Gloria +3 more
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