Results 61 to 70 of about 7,378 (198)

Bowel ultrasound scan in the management of pediatric moderate ulcerative colitis: The applicability of international bowel ultrasound segmental activity score

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 438-446, September 2026.
Abstract Objectives To evaluate bowel ultrasound (BUS) findings and the diagnostic and prognostic performance of international bowel ultrasound segmental activity score (IBUS‐SAS) in children with moderate ulcerative colitis (UC), including its accuracy for assessing endoscopic activity and predicting clinical remission and colectomy within 12 months ...
Martina Di Benedetto   +8 more
wiley   +1 more source

Disease‐Intrinsic Organising Pneumonia During Biomarker‐Confirmed Ulcerative Colitis Remission

open access: yesRespirology Case Reports, Volume 14, Issue 9, September 2026.
Organising pneumonia (OP) can occur as a disease‐intrinsic extraintestinal manifestation of ulcerative colitis (UC) during biochemical remission. Drug‐induced aetiology must be systematically excluded before attributing OP to UC. Cryobiopsy‐based ILD diagnoses require expert pathology review when treatment decisions are consequential, as the ...
Rahaf A. Jereisat   +2 more
wiley   +1 more source

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy

open access: yesAlimentary Pharmacology &Therapeutics, Volume 64, Issue 6, Page 729-747, September 2026.
The gut microbiome modulates ulcerative colitis pharmacotherapy through microbial drug metabolism, immune regulation and altered drug bioavailability. Microbial composition influences response to aminosalicylates, corticosteroids, immunomodulators, biologics and small molecules, while microbiome‐targeted therapies show emerging promise.
Kate Collins   +6 more
wiley   +1 more source

Simple and sensitive spectrophotometric methods for the analysis of mesalamine in bulk and tablet dosage forms

open access: yesQuímica Nova, 2011
Three simple, sensitive, economical and reproducible spectrophotometric methods (A, B and C) are described for determination of mesalamine in pure drug as well as in tablet dosage forms. Method A is based on the reduction of tungstate and/or molybdate in
Bala Sekaran Chandra   +5 more
doaj   +1 more source

The anti-inflammatory drug mesalamine targets bacterial polyphosphate accumulation

open access: yes, 2017
Mesalamine serves as the gold standard in treating ulcerative colitis. However, its precise mechanism(s) of action remains unclear. Here, we show that mesalamine treatment rapidly decreases polyphosphate levels in diverse bacteria, including members of ...
Bazopoulou, D.   +11 more
core   +1 more source

Beyond Glucocorticoids: The Current Landscape and Prospects for Treating Immune Checkpoint Inhibitor‐Induced Autoimmunity

open access: yesACR Open Rheumatology, Volume 8, Issue 8, August 2026.
The rapid integration of immune checkpoint inhibitors (ICIs) into standard oncology protocols has birthed a new frontier in clinical rheumatology: immune‐related adverse events (irAEs). By disrupting the programmed cell death‐1 (PD‐1)/PD‐L1 and cytotoxic T‐lymphocyte‐associated protein 4 (CTLA‐4) axes to restore antitumor T cell activity, these ...
Xizi Hu   +3 more
wiley   +1 more source

Update on the management of ulcerative colitis: treatment and maintenance approaches focused on MMX® mesalamine [PDF]

open access: yes, 2013
Ulcerative colitis (UC) is a chronic inflammatory disease of the colon that typically manifests as diarrhea, abdominal pain, and bloody stool. Complications, such as colorectal cancer and extraintestinal manifestations, may also develop.
Moss, Alan, Nanda, Kavinderjit
core   +1 more source

Effect of Intestinal Microbiota Transplantation on Intestinal Flora and Inflammatory Factor Levels in Patients with Ulcerative Colitis

open access: yesInfection and Drug Resistance, 2023
Zhi Wang,1,* Li Yang,2,* Shan Sun2 1Pediatric Gastrointestinal Surgery, Sinopharm Dongfeng General Hospital, Hubei University of Medicine, Shiyan, People’s Republic of China; 2Gastroenterology, Sinopharm Dongfeng General Hospital, Hubei ...
Wang Z, Yang L, Sun S
doaj  

Corticosteroids and Mesalamine Versus Corticosteroids for Acute Severe Ulcerative Colitis: A Randomized Controlled Trial

open access: yes, 2022
Background & aims: Corticosteroids are the mainstay of treatment for hospitalized patients with acute severe ulcerative colitis (ASUC). However, whether the addition/continuation of mesalamine with corticosteroids during hospitalization is superior to ...
천재희
core   +1 more source

Determination of Mesalamine Related Impurities from Drug Product by Reversed Phase Validated UPLC Method

open access: yesE-Journal of Chemistry, 2011
In the present study gradient reversed-phase UPLC method was developed for simultaneous determination and separation of impurities and degradation products from drug product.
Trivedi Rakshit Kanubhai   +2 more
doaj   +1 more source

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