Results 11 to 20 of about 7,378 (198)

Mesalamine-Induced Myocarditis [PDF]

Cardiology Research and Practice, 2010
Nowadays mesalamine is a common treatment for Crohn's disease and hypersensitive reactions to this product have been reported. Yet there is limited information concerning mesalamine-induced myocarditis and its mechanism is not known.
Olivier Merceron, Clement Bailly, Antoine Khalil, Florence Pontnau, Nadjib Hammoudi, Richard Dorent, Pierre-Louis Michel   +6 more
doaj   +5 more sources

Mesalamine induced eosinophilic pneumonia

Respiratory Medicine Case Reports, 2017
We present the case of a twenty two year old Caucasian male with ulcerative colitis on mesalamine who presented with dry cough, fever, malaise and dyspnea on exertion.
Ankit Gupta, MD, MS, Swati Gulati, MD, MS   +1 more
doaj   +4 more sources

Real-World Adherence and Relapse Risk in Mesalamine Treatment for Ulcerative Colitis: Insights from a Large Japanese Medical Claims Database [PDF]

Inflammatory Intestinal Diseases
Introduction: 5-Aminosalicylic acid (5-ASA, mesalamine) is the cornerstone for maintaining remission in mild-to-moderate ulcerative colitis (UC), with several formulations available.
Takafumi Wada, Shuhei Hosomi, Yumie Kobayashi, Rieko Nakata, Yu Nishida, Hirotsugu Maruyama, Masaki Ominami, Yuji Nadatani, Shusei Fukunaga, Koji Otani, Fumio Tanaka, Yasuhiro Fujiwara   +11 more
doaj   +2 more sources

Significance of the drug-induced lymphocyte stimulation test for various oral mesalamines in ulcerative colitis with mesalamine intolerance. [PDF]

PLoS ONE
This study aimed to determine if the drug-induced lymphocyte stimulation test (DLST) for various oral mesalamines can diagnose mesalamine intolerance and predict the success of retreatment in patients with adverse events (AEs) due to the first oral 5 ...
Akira Madarame, Masakatsu Fukuzawa, Kumiko Uchida, Tadashi Ichimiya, Sakiko Naito, Yoshiya Yamauchi, Takashi Morise, Yasuyuki Kagawa, Takahiro Muramatsu, Takao Itoi   +9 more
doaj   +2 more sources

Translational Modeling of Gut Microbiome‐Mediated Drug Metabolism: A Case Example of Sulfasalazine [PDF]

CPT: Pharmacometrics & Systems Pharmacology
The gut microbiome can contribute to drug metabolism and significantly influence pharmacokinetic (PK) behavior. Sulfasalazine is well‐known to be metabolized by gut bacterial azoreductases into sulfapyridine and mesalamine.
Lisa Cheng, Jingwei Cai, Alexis Auster, Sungjoon Cho, Mary Keir, Horace Rhee, Bennett Kapili, Dari Shalon, Miaoran Ning   +8 more
doaj   +2 more sources

Recurrent pleuropericarditis associated with mesalazine therapy masked by steroid use [PDF]

European Journal of Case Reports in Internal Medicine
Introduction: Mesalazine is a cornerstone therapy for ulcerative colitis (UC). Although generally safe, it can cause rare but life-threatening cardiopulmonary complications such as pleuropericarditis.
Hakan Demiröz, Hasan Eruzun, Handan Doğan Çakmak, Aydın Can Ulusoy, Yusuf Bünyamin Ketenci, Mehmet Akca, Ahmet Bektaş   +6 more
doaj   +2 more sources

Adjunctive Pentoxifylline Enhances Clinical Remission and Reduces Inflammatory Biomarkers in Mild-to-Moderate Ulcerative Colitis: A Randomized Double-Blind Placebo-Controlled Pilot Trial [PDF]

Pharmaceuticals
Background: Despite mesalamine’s efficacy in mild-to-moderate ulcerative colitis (UC), many patients fail to achieve complete clinical or biochemical remission.
Mohannad O. Khrieba, Furqan M. Abdulelah, Amal Mohammed Badawoud, Eman Hamza, Reham A. Al-Dhelaan, Tarek I. Ahmed, Ahmed G. Abdelhameed, Nora Elshorbagi, Doaa A. El-Hanafy, Nashwa Eltantawy, Muhammed M. Salahuddin, Noha M. Elkhodary, Kholoud H. Radwan, Khaled Abo Bakr Khalaf Ali, Abeer A. El-Sayed, Marwa Kamal   +15 more
doaj   +2 more sources

Oral 5-Aminosalicylate, Mesalamine Suppository, and Mesalamine Enema as Initial Therapy for Ulcerative Proctitis in Clinical Practice with Quality of Care Implications [PDF]

Canadian Journal of Gastroenterology and Hepatology, 2016
Background. Ulcerative proctitis (UP) is typically treated initially with oral 5-aminosalicylate (“5-ASA”), mesalamine suppository, or mesalamine enema (“UP Rx”). Little is known about their effectiveness in practice. Methods. Using a US health insurance
James M. Richter, Nabeela K. Arshi, Gerry Oster   +2 more
doaj   +2 more sources

A novel pH–enzyme-dependent mesalamine colon-specific delivery system

Drug Design, Development and Therapy, 2016
Lei Jin, Yi-cun Ding, Yu Zhang, Xiao-qing Xu, Qin Cao Department of Gastroenterology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China Abstract: The aim of the present study was to ...
Jin L, Ding Y, Zhang Y, Xu X, Cao Q
doaj   +1 more source

Myocarditis Secondary to Mesalamine-Induced Cardiotoxicity in a Patient with Ulcerative Colitis [PDF]

Case Reports in Medicine, 2018
Development of cardiac manifestations in patients diagnosed with inflammatory bowel disease undergoing treatment with mesalamine is a rare. When this occurs, it can be difficult to tease out the primary etiology, as both IBD and mesalamine can cause ...
Kelechukwu U. Okoro, Matthew D. Roby, Adegbenga A. Bankole   +2 more
doaj   +2 more sources