SMALL ORGAN4 Is a Ribosome Biogenesis Factor Involved in 5.8S Ribosomal RNA Maturation [PDF]
Ribosome biogenesis is crucial for cellular metabolism and has important implications for disease and aging. Human (Homo sapiens) glioma tumor-suppressor candidate region gene2 (GLTSCR2) and yeast (Saccharomyces cerevisiae) Nucleolar protein53 (Nop53) are orthologous proteins with demonstrated roles as ribosome biogenesis factors; knockdown of GLTSCR2 ...
Rosa Micol‐Ponce+6 more
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Insecticidal activity of three 10–12 nucleotides long antisense sequences from 5.8S ribosomal RNA gene of gypsy moth Lymantria dispar L. against its larvae [PDF]
5.8S ribosomal RNA plays an important role in protein synthesis and eukaryotic ribosome translocation. Contact DNA insecticides based on antisense fragments of 5.8S ribosomal RNA gene of gypsy moth Lymantria dispar L.
Volodymyr V. Oberemok+9 more
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Inhibition of protein synthesis by an efficiently expressed mutation in the yeast 5.8S ribosomal RNA [PDF]
Recent studies on the inhibition of protein synthesis by specific anti 5.8S rRNA oligonucleotides strongly suggested that this RNA plays an important role in eukaryotic ribosome function. To evaluate this possibility further, a ribosomal DNA transcription unit from Schizosaccharomyces pombe was cloned into yeast shuttle vectors with copy numbers ...
Sherif Abou Elela+3 more
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Transcriptional organization of the 5.8S ribosomal RNA ristron in Xenopus laevis ribosomal DNA
Hybridization of purified, 32p-labeled 5.8S ribosomal RNA from Xenopus laevis to fragments generated from X. laevis rDNA by the restriction endonuclease, EcoRI, demonstrates that the 5.8S rRNA cistron lies within the transcribed region that links the 18S and 28S rRNA cistrons.
Thomas A. Walker, Norman R. Pace
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The 5.8S RNA gene sequence and the ribosomal repeat ofSchizosaccharomyces pombe
We have characterized the rRNA gene repeat in Schizosaccharomyces pombe. This repeat, which does not contain the 5S RNA gene, is found in a 10.4 kb HindIII DNA fragment. We have determined the nucleotide sequences of the S. pombe 5.8S RNA gene and intergenic spacers from two different 10.4 kb DNA fragments.
Jerome Schaak, Jen-i Mao, Dieter Söll
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The 5.8S ribosomal RNA gene ofTrypannsoma brucei: structural and transciiptional studies [PDF]
To further investigate the process of discontinuous transcription in trypanosomes, the 5.8S rRNA gene, present in the trypanosome genome as part of the multicopy rRNA gene cluster, has been cloned, sequenced, chromosomally mapped, and used in transcriptional studies.
David M. Dorfman+4 more
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A Reassessment of Phylogenetic Relationships in Class Oligohymenophorea (Protista, Ciliophora) Based on Updated Multigene Data [PDF]
Within the ciliate class Oligohymenophorea, many evolutionary relationships among taxa remain unresolved. This study incorporates 97 new sequences from 30 oligohymenophorean populations, including nuclear small subunit ribosomal (SSU‐rRNA) genes, nuclear
Bailin Li+7 more
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Nucleotide sequence of an exceptionally long 5.8S ribosomal RNA from Crithidia fasciculata [PDF]
In Crithidia fasciculata, a trypanosomatid protozoan, the large ribosomal subunit contains five small RNA species (e, f, g, i, j) in addition to 5S rRNA [Gray, M.W. (1981) Mol. Cell. Biol. 1, 347-357]. The complete primary sequence of species i is shown here to be pAACGUGUmCGCGAUGGAUGACUUGGCUUCCUAUCUCGUUGA ...
Murray N. Schnare, Michael W. Gray
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Exploring the roles of snoRNA-induced ribosome heterogeneity in equine osteoarthritis [PDF]
IntroductionOsteoarthritis (OA) is a degenerative joint disease that greatly contributes to equine morbidity and poor welfare. Changes in cellular protein expression programs fuel the development and progression of OA.
Alzbeta Chabronova+6 more
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An improved direct RNA sequence method; its application to Vida faba 5.8S ribosomal RNA
We have developed a direct read-off sequencing procedure, based on the method of Stanley and Vassilenko using E. coli 5S ribosomal RNA as a model compound. Radioactive bands were transferred from an acrylamide gel fractionation in the first dimension onto a DEAE-cellulose thin layer plate. After in situ enzymatic digestion with RNase T2, mononucleoside
Yuya Tanaka+2 more
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