Results 1 to 10 of about 887,234 (267)

Brain antibody sequence evaluation (BASE): an easy-to-use software for complete data analysis in single cell immunoglobulin cloning

BMC Bioinformatics, 2020
Background Repertoire analysis of patient-derived recombinant monoclonal antibodies is an important tool to study the role of B cells in autoimmune diseases of the human brain and beyond.
S. Momsen Reincke, Harald Prüss, Jakob Kreye   +2 more
doaj   +1 more source

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries. [PDF]

PLoS ONE, 2018
The design of highly diverse phage display libraries is based on assumption that DNA bases are incorporated at similar rates within the randomized sequence.
Steven Shave, Stefan Mann, Joanna Koszela, Alastair Kerr, Manfred Auer   +4 more
doaj   +1 more source

Gröbner Bases for Increasing Sequences

The Electronic Journal of Combinatorics
Let $q,n \geq 1$ be integers, $[q]=\{1,\ldots, q\}$, and $F$ be a field with $|F|\geq q$. The setof increasing sequences $$I(n,q)=\{(f_1,f_2, \dots, f_n) \in [q]^n:~ f_1\leq f_2\leq\cdots \leq f_n \}$$can be mapped via an injective map $i: [q]\rightarrow F $ into a subset $J(n,q)$ of the affine space $F^n$.
Hegedüs, Gábor, Rónyai, Lajos
openaire   +3 more sources

بررسی بیوانفورماتیک ارتباط اندازه‌ی ژنوم با خصوصیات ژنتیکی و رفتاری باکتری‌های بیماری‌زا

مجله دانشکده پزشکی اصفهان, 2014
مقدمه: با افزایش تعداد باکتری‌هایی که توالی‌یابی می‌شوند، نیاز به بهره‌برداری از این داده‌ها نیز بیشتر می‌شود. استفاده از این اطلاعات ژنومی از طریق به کارگیری هم‌زمان علوم بیوانفورماتیک و باکتری‌شناسی امکان‌ پذیر می‌باشد.
Mohammad Reza Pourmand, Zahra Pakbaz, Abbas Rahimi-Foroushani, Solmaz Ohadian-Moghadam   +3 more
doaj  

Diagnostic value of 3D-Cube T2 sequence combined with plain CT scan of the skull base for cerebrospinal fluid rhinorrhea

Di-san junyi daxue xuebao, 2019
Objective To evaluate the diagnostic value of magnetic resonance 3D-Cube T2 sequence, plain CT scan of the skull base and their combination for cerebrospinal fluid (CSF) rhinorrhea and assess the performance of these 2 modalities combined in improving ...
GAN Hui, ZHANG Song, JIANG Liling, GE Xiaodong, ZOU Liguang   +4 more
doaj   +1 more source

Improving the specificity of nucleic acid detection with endonuclease-actuated degradation

Communications Biology, 2022
A new method, SENTINEL, improves the specificity of nucleic acid target sequence identification via a combination of isothermal amplification and sequence-specific DNA endonucleases. The method can discriminate single base-pair differences and takes less
Roger S. Zou, Momcilo Gavrilov, Yang Liu, Dominique Rasoloson, Madison Conte, Justin Hardick, Leo Shen, Siqi Chen, Andrew Pekosz, Geraldine Seydoux, Yukari C. Manabe, Taekjip Ha   +11 more
doaj   +1 more source

The complete mitogenome and phylogenetic analysis of Japanese firefly ‘Genji Botaru’ Luciola cruciata (Coleoptera: Lampyridae)

Mitochondrial DNA. Part B. Resources, 2017
We performed mitogenome analysis of Japanese firefly Luciola cruciata (Coleoptera: Lampyridae), which is unique species in Japan. It is classified into six haplotypes based on the difference of COII sequence on mitochondrial DNA.
Juri Maeda, Dai-ichiro Kato, Kazunari Arima, Yuji Ito, Atsushi Toyoda, Hideki Noguchi   +5 more
doaj   +1 more source

Contribution of nonconsensus base pairs within ArsR binding sequences toward ArsR-DNA binding and arsenic-mediated transcriptional induction

Journal of Biological Engineering, 2019
Background A transcriptional reporter is the key component in bacterial biosensors which are employed to monitor the induction or repression of a reporter gene corresponding to environmental change.
Xingjuan Chen, Xin Jiang, Cuijuan Tie, Jinnon Yoo, Yan Wang, Meiying Xu, Guoping Sun, Jun Guo, Xianqiang Li   +8 more
doaj   +1 more source

Evolution regularity of the Neogene shallow water delta in the Laibei area Bohai Bay Basin, northern China

Journal of Palaeogeography, 2014
According to the characteristics of sedimentary microfacies, unique vertical depositional sequences and well logging response, the authors propose that a shallow water delta was widely developed in the Neogene of the Laibei area, Bohai Bay Basin of ...
Jian-Ping Li, Hao Liu, Cheng-Min Niu, Rui-Bo Guo   +3 more
doaj   +1 more source

Key controls of the gas and oil preferences of China's major coal-bearing sequences

Petroleum Exploration and Development, 2009
The key controls on the gas and oil preferences of coal-bearing strata are discussed from the relationship of material foundation between coal formation and hydrocarbon generation, the variation of the initial gas to oil ratio (GOR) of organic matter in ...
Zhong Ningning, Chen Gongyang
doaj   +1 more source