Results 31 to 40 of about 6,391,316 (304)
Sequence-Directed Control of Cyanine Dye Stacking Geometry within DNA Duplexes. [PDF]
JACS AuThe photophysical properties of dye aggregates are governed by their supramolecular stacking geometries, such as H- and J-type arrangements. Structural DNA nanotechnology provides a programmable platform for the spatially precise organization of ...
Wang Y, Cui N, Fang W.
europepmc +2 more sources
Sequence-dependent base pair stepping dynamics in XPD helicase unwinding
eLife, 2013 Helicases couple the chemical energy of ATP hydrolysis to directional translocation along nucleic acids and transient duplex separation. Understanding helicase mechanism requires that the basic physicochemical process of base pair separation be ...
Zhi Qi +3 more
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Life, 2022 DNA carries more than the list of biochemical ingredients that drive the basic functions of living systems. The sequence of base pairs includes a multitude of structural and energetic signals, which determine the degree to which the long, threadlike ...
Robert T. Young +4 more
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Base-By-Base Version 3: New Comparative Tools for Large Virus Genomes
Viruses, 2018 Base-By-Base is a comprehensive tool for the creation and editing of multiple sequence alignments that is coded in Java and runs on multiple platforms. It can be used with gene and protein sequences as well as with large viral genomes, which themselves ...
Shin-Lin Tu +5 more
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DddA homolog search and engineering expand sequence compatibility of mitochondrial base editing
Nature Communications, 2023 There is a need to improve and expand mitochondrial base editing tools. Here the authors identify a DddA homolog from Simiaoa sunii (Ddd_Ss) which can efficiently deaminate cytosine in dsDNA; they develop cytosine base editors and introduce mutations at ...
Li Mi +13 more
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Journal of FungiThis study included 24 isolates of the Candidozyma haemuli species complex from patients in the Brazilian Amazon between 2021 and 2024. These isolates were identified by sequencing as C. duobushaemuli (54.2%), C. haemuli sensu stricto (29.2%), C. haemuli
Sérgio Lobato França +7 more
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Effect of Base Sequence on G-Wire Formation in Solution
Journal of Nucleic Acids, 2010 The formation and dimensions of G-wires by different short G-rich DNA sequences in solution were investigated by dynamic light scattering (DLS) and polyacrilamide gel electrophoresis (PAGE).
Lea Spindler +4 more
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Peak Height Pattern in Dichloro-Rhodamine and Energy Transfer Dye Terminator Sequencing
BioTechniques, 1998 Establishing the pattern in peak heights within local sequence contexts improves the accuracy of base calling and the identification of DNA sequence variations in dye-terminator cycle sequencing.
H. Zakeri +4 more
doaj +1 more source
Journal of Nucleic Acids, 2023 MGB polyamide-oligonucleotide conjugates ON 1-4 with linked MGB polyamides at the 2-exocyclic amino group of a guanine base using aminoalkyl linkers were synthesized and evaluated in terms of binding affinity for complementary DNA containing the MGB ...
Kazuo Kamaike +13 more
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Contact-based sequence alignment [PDF]
Nucleic Acids Research, 2004 This paper introduces the novel method of contact-based protein sequence alignment, where structural information in the form of contact mutation probabilities is incorporated into an alignment routine using contact-mutation matrices (CAO: Contact Accepted mutatiOn).
Kleinjung, J. +3 more
openaire +3 more sources