Results 51 to 60 of about 5,824 (218)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

بررسی بیوانفورماتیک ارتباط اندازه‌ی ژنوم با خصوصیات ژنتیکی و رفتاری باکتری‌های بیماری‌زا

مجله دانشکده پزشکی اصفهان, 2014
مقدمه: با افزایش تعداد باکتری‌هایی که توالی‌یابی می‌شوند، نیاز به بهره‌برداری از این داده‌ها نیز بیشتر می‌شود. استفاده از این اطلاعات ژنومی از طریق به کارگیری هم‌زمان علوم بیوانفورماتیک و باکتری‌شناسی امکان‌ پذیر می‌باشد.
Mohammad Reza Pourmand, Zahra Pakbaz, Abbas Rahimi-Foroushani, Solmaz Ohadian-Moghadam   +3 more
doaj  

Research of Dynamic Wide-gap Frequency Hopping Sequences in Dynamic Spectrum Anti-jamming System [PDF]

Jisuanji gongcheng, 2018
The existing Frequency Hopping(FH) sequence can not be directly applied to a dynamic spectrum anti-interference system due to poor statistical performance and difficulty in real-time changes of communication parameters.Therefore,a FH sequence suitable ...
LI Shengnan,LI Yonggui,NIU Yingtao,YAN Yan,LUO Jianxiang
doaj  

Complete mitochondrial genome sequence of tufted deer (Elaphodus cephalophus) with phylogenetic analysis

Mitochondrial DNA. Part B. Resources, 2019
The complete mitochondrial genome of tufted deer (Elaphodus cephalophus) has been described in our research. The sequence of this genome is 16356 bp with a circular structure, and contains 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two
Lin Zhang, Yongfang Yao, Diyan Li, Jiayun Wu, Anxiang Wen, Meng Xie, Qin Wang, Guangxiang Zhu, Qingyong Ni, Mingwang Zhang, Huailiang Xu   +10 more
doaj   +1 more source

Brain antibody sequence evaluation (BASE): an easy-to-use software for complete data analysis in single cell immunoglobulin cloning

BMC Bioinformatics, 2020
Background Repertoire analysis of patient-derived recombinant monoclonal antibodies is an important tool to study the role of B cells in autoimmune diseases of the human brain and beyond.
S. Momsen Reincke, Harald Prüss, Jakob Kreye   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning

Synthetic and Systems Biotechnology
Base substitution, insertion, and deletion errors due to inherent technical constraints inducing unavoidable sequencing inaccuracies, limiting access to high-quality raw data and biological knowledge.
Xue Li, Yanfen Zheng, Qi Shao, Jiadong Wang, Wei Li, Bin Wang, Shihua Zhou, Ben Cao, Pan Zheng   +8 more
doaj   +1 more source

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries. [PDF]

PLoS ONE, 2018
The design of highly diverse phage display libraries is based on assumption that DNA bases are incorporated at similar rates within the randomized sequence.
Steven Shave, Stefan Mann, Joanna Koszela, Alastair Kerr, Manfred Auer   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

High-Utility Interval-Based Sequences [PDF]

, 2020
To appear in Proceedings of the 22nd International Conference on Big Data Analytics and Knowledge Discovery (DaWaK2020), Bratislava, Slovakia, September 14-17.
S. Mohammad Mirbagheri, Howard J. Hamilton   +1 more
openaire   +2 more sources