Early-onset ischaemic stroke in a patient with the novel F2 c.1824C>T gene variant and PAI-1 4G/4G, MTHFR 677TT genotype [PDF]
Vojnosanitetski Pregled, 2022 Introduction. Ischemic stroke (IS) is a heterogeneous dis-order caused by several genetic and environmental risk factors. It was suggested that coagulation disorders cause 1-4% of cases with IS, especially in patients with early onset of IS. Case report.
Pruner Iva +5 more
doaj +1 more source
Distinguishing regional from within-codon rate heterogeneity in DNA sequence alignments [PDF]
, 2009 We present an improved phylogenetic factorial hidden Markov model (FHMM) for detecting two types of mosaic structures in DNA sequence alignments, related to (1) recombination and (2) rate heterogeneity.
Husmeier, D. +4 more
core +5 more sources
Addressing the shortcomings of three recent bayesian methods for detecting interspecific recombination in DNA sequence alignments [PDF]
, 2008 We address a potential shortcoming of three probabilistic models for detecting interspecific recombination in DNA sequence alignments: the multiple change-point model (MCP) of Suchard et al. (2003), the dual multiple change-point model (DMCP) of Minin et
Mantzaris, Alexander Vassilios +1 more
core +4 more sources
Sequencing analysis of HPV-other type on an HPV DNA chip [PDF]
Obstetrics & Gynecology Science, 2018 ObjectivesTo identify the specific human papillomavirus (HPV) genotypes from HPV-other type on an HPV DNA chip test by sequencing.MethodsAmong 13,600 women undergoing a routine gynecology examination including Pap smear and/or HPV test by DNA chip test ...
Min-Jeong Kim, Jin Ju Kim, Sunmie Kim
doaj +1 more source
Variants of CARD14 gene and psoriasis vulgaris in southern Chinese cohort [PDF]
Anais Brasileiros de Dermatologia, 2016 BACKGROUND: Recent mutation analysis identified several missense mutations in CARD14 in psoriasis. OBJECTIVES: We performed the genomic sequence analysis on CARD14 in southern Chinese Han Cantonese with Psoriasis Vulgaris (PsV) to reveal more causative ...
Kunju Zhu +4 more
doaj +1 more source
Clonal leukemic evolution in myelodysplastic syndromes with TET2 and IDH1/2 mutations
Haematologica, 2014 Somatic mutations of TET2, IDH1, and IDH2 have been described in myelodysplastic syndrome. The impact of these mutations on outcome of myelodysplastic syndrome and their progression to secondary acute myeloid leukemia remains unclear.
Tung-Liang Lin +18 more
doaj +1 more source
A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei [PDF]
, 1992 Tissue-specific patterns of methylated deoxycytidine residues in the mammalian genome are preserved by postreplicative methylation of newly synthesized DNA. DNA methyltransferase (MTase) is here shown to associate with replication foci during S phase but
Heinz-Ulrich Weier +14 more
core +1 more source
Sequencing and Analysis of Neanderthal Genomic DNA [PDF]
Science, 2006 Our knowledge of Neanderthals is based on a limited number of remains and artifacts from which we must make inferences about their biology, behavior, and relationship to ourselves. Here, we describe the characterization of these extinct hominids from a new perspective, based on the development of a Neanderthal metagenomic library ...
Noonan, James P. +10 more
openaire +6 more sources
Comparative Viral Metagenomics of Environmental Samples from Korea [PDF]
Genomics & Informatics, 2013 The introduction of metagenomics into the field of virology has facilitated the exploration of viral communities in various natural habitats. Understanding the viral ecology of a variety of sample types throughout the biosphere is important per se, but ...
Min-Soo Kim, Tae Woong Whon, Jin-Woo Bae
doaj +1 more source
A Complete Mitochondrial Genome Sequence from a Mesolithic Wild Aurochs (Bos primigenius) [PDF]
, 2010 Background The derivation of domestic cattle from the extinct wild aurochs (Bos primigenius) has been well-documented by archaeological and genetic studies.
Finlay Emma K. +63 more
core +1 more source