Results 11 to 20 of about 26,765,029 (301)

DNA sequence analysis of SLC26A5, encoding prestin, in a patient-control cohort: identification of fourteen novel DNA sequence variations. [PDF]

open access: yesPLoS ONE, 2009
Prestin, encoded by the gene SLC26A5, is a transmembrane protein of the cochlear outer hair cell (OHC). Prestin is required for the somatic electromotile activity of OHCs, which is absent in OHCs and causes severe hearing impairment in mice lacking ...
Jacob S Minor   +3 more
doaj   +1 more source

Genome analysis of a Glossina pallidipes salivary gland hypertrophy virus reveals a novel, large, double-stranded circular DNA virus [PDF]

open access: yes, 2008
Several species of tsetse flies can be infected by the Glossina pallidipes salivary gland hypertrophy virus (GpSGHV). Infection causes salivary gland hypertrophy and also significantly reduces the fecundity of the infected flies. To better understand the
Parker, Andrew G.   +17 more
core   +1 more source

Comparative analyses of classical phenotypic method and ribosomal RNA gene sequencing for identification of medically relevant Candida species

open access: yesMemorias do Instituto Oswaldo Cruz, 2013
As the distribution of Candida species and their susceptibility to antifungal agents have changed, a new means of accurately and rapidly identifying these species is necessary for the successful early resolution of infection and the subsequent reduction ...
Constanza Giselle Taverna   +6 more
doaj   +1 more source

Copper Ions Induce DNA Sequence Variation in Zygotic Embryo Culture-Derived Barley Regenerants

open access: yesFrontiers in Plant Science, 2021
In vitro tissue culture could be exploited to study cellular mechanisms that induce sequence variation. Altering the metal ion composition of tissue culture medium affects biochemical pathways involved in tissue culture-induced variation. Copper ions are
Renata Orłowska   +2 more
doaj   +1 more source

Zinc finger recombinases with adaptable DNA sequence specificity [PDF]

open access: yes, 2011
Site-specific recombinases have become essential tools in genetics and molecular biology for the precise excision or integration of DNA sequences. However, their utility is currently limited to circumstances where the sites recognized by the recombinase ...
Proudfoot, C.   +19 more
core   +1 more source

A Deep Learning Model for Predicting DNA N6-Methyladenine (6mA) Sites in Eukaryotes

open access: yesIEEE Access, 2020
DNA N6-methyladenine (6mA) is an epigenetic modification, which is involved in many biological regulation processes like DNA replication, DNA repair, transcription, and gene expression regulation.
Lokuthota Hewage Roland   +1 more
doaj   +1 more source

Completely mitochondrial genome of Neolissochilus heterostomus

open access: yesMitochondrial DNA. Part B. Resources, 2021
In this study, we determined the complete mitochondrial genome of Neolissochilus heterostomus. The genome is 16,585 bp in length, including 2 ribosomal RNA genes, 13 proteins-coding genes, 22 transfer RNA genes, and two non-coding control regions ...
Jinghong He   +5 more
doaj   +1 more source

Towards precision quantification of contamination in metagenomic sequencing experiments

open access: yesMicrobiome, 2019
Metagenomic next-generation sequencing (mNGS) experiments involving small amounts of nucleic acid input are highly susceptible to erroneous conclusions resulting from unintentional sequencing of occult contaminants, especially those derived from ...
M. S. Zinter   +4 more
doaj   +1 more source

Preferential access to genetic information from endogenous hominin ancient DNA and accurate quantitative SNP-typing via SPEX [PDF]

open access: yes, 2009
The analysis of targeted genetic loci from ancient, forensic and clinical samples is usually built upon polymerase chain reaction (PCR)-generated sequence data.
Endicott, Phillip   +8 more
core   +1 more source

High-Throughput DNA Analysis Platform Based on an Optofluidic Ring Resonator Laser

open access: yesApplied Sciences, 2022
We demonstrate an optofluidic laser using DNA microdroplets, an intercalating dye, and a glass capillary ring resonator. Only the target DNA emits the laser signal, while the non-target DNA, including those with single-base mismatches, exhibits zero ...
Chan Seok Jun, Wonsuk Lee
doaj   +1 more source

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