Results 71 to 80 of about 965,609 (309)

Integrated multiple sequence alignment [PDF]

open access: yes, 2005
Sammeth M. Integrated multiple sequence alignment. Bielefeld (Germany): Bielefeld University; 2005.The thesis presents enhancements for automated and manual multiple sequence alignment: existing alignment algorithms are made more easily accessible and ...
Sammeth, Michael
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

بررسی بیوانفورماتیک ارتباط اندازه‌ی ژنوم با خصوصیات ژنتیکی و رفتاری باکتری‌های بیماری‌زا

open access: yesمجله دانشکده پزشکی اصفهان, 2014
مقدمه: با افزایش تعداد باکتری‌هایی که توالی‌یابی می‌شوند، نیاز به بهره‌برداری از این داده‌ها نیز بیشتر می‌شود. استفاده از این اطلاعات ژنومی از طریق به کارگیری هم‌زمان علوم بیوانفورماتیک و باکتری‌شناسی امکان‌ پذیر می‌باشد.
Mohammad Reza Pourmand   +3 more
doaj  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The RNA Ontology (RNAO): An ontology for integrating RNA sequence and structure data [PDF]

open access: yes, 2009
Biomedical Ontologies are intended to integrate diverse biomedical data to enable intelligent data-mining and facilitate translation of basic research into useful clinical knowledge.
Eric Westhof   +9 more
core   +1 more source

Highly biased DNA sequence reconstruction in DNA storage with multi-scale attention mechanism and contrast learning

open access: yesSynthetic and Systems Biotechnology
Base substitution, insertion, and deletion errors due to inherent technical constraints inducing unavoidable sequencing inaccuracies, limiting access to high-quality raw data and biological knowledge.
Xue Li   +8 more
doaj   +1 more source

Research of Dynamic Wide-gap Frequency Hopping Sequences in Dynamic Spectrum Anti-jamming System [PDF]

open access: yesJisuanji gongcheng, 2018
The existing Frequency Hopping(FH) sequence can not be directly applied to a dynamic spectrum anti-interference system due to poor statistical performance and difficulty in real-time changes of communication parameters.Therefore,a FH sequence suitable ...
LI Shengnan,LI Yonggui,NIU Yingtao,YAN Yan,LUO Jianxiang
doaj  

Sequence-dependent nucleosome sliding in rotation-coupled and uncoupled modes revealed by molecular simulations. [PDF]

open access: yesPLoS Computational Biology, 2017
While nucleosome positioning on eukaryotic genome play important roles for genetic regulation, molecular mechanisms of nucleosome positioning and sliding along DNA are not well understood.
Toru Niina   +3 more
doaj   +1 more source

High-Utility Interval-Based Sequences [PDF]

open access: yes, 2020
To appear in Proceedings of the 22nd International Conference on Big Data Analytics and Knowledge Discovery (DaWaK2020), Bratislava, Slovakia, September 14-17.
S. Mohammad Mirbagheri   +1 more
openaire   +2 more sources

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