Results 81 to 90 of about 965,609 (309)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Sequence- and Stereospecific Conformational Rearrangement of Styrene Oxide Adducts Located at A·C Mismatched Base Pairs [PDF]

open access: yes, 2016
The solution structures of R- and S-α-(N6-adenyl)-styrene oxide adducts mismatched with cytosine at position X7 in d(CGGACAXGAAG)·d(CTTCCTGTCCG), incorporating codons 60, 61 (underlined), and 62 of the human N-ras protooncogene, were determined.
Amanda S. Wilkinson (2945667)   +5 more
core   +1 more source

Complete mitochondrial genome sequence of tufted deer (Elaphodus cephalophus) with phylogenetic analysis

open access: yesMitochondrial DNA. Part B. Resources, 2019
The complete mitochondrial genome of tufted deer (Elaphodus cephalophus) has been described in our research. The sequence of this genome is 16356 bp with a circular structure, and contains 13 protein-coding genes (PCGs), 22 transfer RNA (tRNA) genes, two
Lin Zhang   +10 more
doaj   +1 more source

Brain antibody sequence evaluation (BASE): an easy-to-use software for complete data analysis in single cell immunoglobulin cloning

open access: yesBMC Bioinformatics, 2020
Background Repertoire analysis of patient-derived recombinant monoclonal antibodies is an important tool to study the role of B cells in autoimmune diseases of the human brain and beyond.
S. Momsen Reincke   +2 more
doaj   +1 more source

Sequence-based abstract interpretation of Prolog [PDF]

open access: yesTheory and Practice of Logic Programming, 2001
Abstract interpretation is a general methodology for systematic development of program analyses. An abstract interpretation framework is centered around a parametrized non-standard semantics that can be instantiated by various domains to approximate different program properties.
LE CHARLIER B   +2 more
openaire   +3 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Sequence-selective detection of double-stranded DNA sequences using pyrrole-imidazole polyamide microarrays [PDF]

open access: yes, 2013
We describe a microarray format that can detect double-stranded DNA sequences with a high degree of sequence selectivity. Cyclooctyne-derivatized pyrrole imidazole polyamides were immobilized on azide-modified glass substrates using microcontact printing
Jonathan M. Cooper (165471)   +5 more
core   +2 more sources

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries. [PDF]

open access: yesPLoS ONE, 2018
The design of highly diverse phage display libraries is based on assumption that DNA bases are incorporated at similar rates within the randomized sequence.
Steven Shave   +4 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Sequence-Dependent Persistence Lengths of DNA [PDF]

open access: yes, 2017
A Monte Carlo code applied to the cgDNA coarse-grain rigid-base model of B-form double-stranded DNA is used to predict a sequence-averaged persistence length of lF = 53.5 nm in the sense of Flory, and of lp = 160 bp or 53.5 nm in the sense of apparent ...
John H. Maddocks (3859951)   +8 more
core   +1 more source

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