Results 91 to 100 of about 6,213,636 (307)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

PuLSE: Quality control and quantification of peptide sequences explored by phage display libraries. [PDF]

PLoS ONE, 2018
The design of highly diverse phage display libraries is based on assumption that DNA bases are incorporated at similar rates within the randomized sequence.
Steven Shave, Stefan Mann, Joanna Koszela, Alastair Kerr, Manfred Auer   +4 more
doaj   +1 more source

A thread-tag based semantics for sequence diagrams [PDF]

, 2007
The sequence diagram is one of the most popular behaviour modelling languages which offers an intuitive and visual way of describing expected behaviour of object-oriented software.
Dan, H, Robert M. Hierons, Haitao Dan, Steve Counsell, Hierons, RM, Counsell, S   +5 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Diagnostic value of 3D-Cube T2 sequence combined with plain CT scan of the skull base for cerebrospinal fluid rhinorrhea

Di-san junyi daxue xuebao, 2019
Objective To evaluate the diagnostic value of magnetic resonance 3D-Cube T2 sequence, plain CT scan of the skull base and their combination for cerebrospinal fluid (CSF) rhinorrhea and assess the performance of these 2 modalities combined in improving ...
GAN Hui, ZHANG Song, JIANG Liling, GE Xiaodong, ZOU Liguang   +4 more
doaj   +1 more source

Improving the specificity of nucleic acid detection with endonuclease-actuated degradation

Communications Biology, 2022
A new method, SENTINEL, improves the specificity of nucleic acid target sequence identification via a combination of isothermal amplification and sequence-specific DNA endonucleases. The method can discriminate single base-pair differences and takes less
Roger S. Zou, Momcilo Gavrilov, Yang Liu, Dominique Rasoloson, Madison Conte, Justin Hardick, Leo Shen, Siqi Chen, Andrew Pekosz, Geraldine Seydoux, Yukari C. Manabe, Taekjip Ha   +11 more
doaj   +1 more source

Novel high-resolution characterization of ancient DNA reveals C > U-type base modification events as the sole cause of post mortem miscoding lesions [PDF]

, 2007
Ancient DNA (aDNA) research has long depended on the power of PCR to amplify trace amounts of surviving genetic material from preserved specimens. While PCR permits specific loci to be targeted and amplified, in many ways it can be intrinsically unsuited
Endicott, Phillip, Cooper, Alan, Austin, J., Juan J. Sanchez, Ross Barnett, Brotherton, Paul, Barnett, Ross, Mark Beaumont, Sanchez, J., Beaumont, Mark, Sanchez, Juan J, Austin, Jeremy, Alan Cooper, Brotherton, P., Sanchez, Juan J., Cooper, A., Jeremy Austin, Paul Brotherton, Beaumont, M., Endicott, P., Barnett, R., Phillip Endicott, Sanchez, J. J.   +22 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Contribution of nonconsensus base pairs within ArsR binding sequences toward ArsR-DNA binding and arsenic-mediated transcriptional induction

Journal of Biological Engineering, 2019
Background A transcriptional reporter is the key component in bacterial biosensors which are employed to monitor the induction or repression of a reporter gene corresponding to environmental change.
Xingjuan Chen, Xin Jiang, Cuijuan Tie, Jinnon Yoo, Yan Wang, Meiying Xu, Guoping Sun, Jun Guo, Xianqiang Li   +8 more
doaj   +1 more source