Results 31 to 40 of about 12,098 (230)

U8 variants on the brain: a small nucleolar RNA and human disease

open access: yesRNA Biology, 2022
Small nucleolar RNAs (snoRNAs) are non-coding RNAs vital for ribosomal RNA (rRNA) maturation. The U8 snoRNA, encoded by the SNORD118 gene in humans, is an atypical C/D box snoRNA as it promotes rRNA cleavage rather than 2′–O–methylation and is unique to ...
Emily J. McFadden, Susan J. Baserga
doaj   +1 more source

Mediating Ribosomal Competition by Splitting Pools [PDF]

open access: yesLCSS Vol 5 Issue 5 (Nov 2020), 2020
Synthetic biology constructs often rely upon the introduction of "circuit" genes into host cells, in order to express novel proteins and thus endow the host with a desired behavior. The expression of these new genes "consumes" existing resources in the cell, such as ATP, RNA polymerase, amino acids, and ribosomes. Ribosomal competition among strands of
arxiv   +1 more source

A New Specific and Sensitive RT-qPCR Method Based on Splinted 5′ Ligation for the Quantitative Detection of RNA Species Shorter than microRNAs

open access: yesNon-Coding RNA, 2021
Recently, we discovered a new family of unusually short RNAs mapping to 5.8S ribosomal RNA (rRNA) and which we named dodecaRNAs (doRNAs), according to the number of core nucleotides (12 nt) their members contain.
Marine Lambert   +2 more
doaj   +1 more source

The sequence of the 5.8 S ribosomal RNA of the crustaceanArtemia salina. With a proposal for a general secondary structure model for 5.8 S ribosomal RNA [PDF]

open access: yesNucleic Acids Research, 1982
We report the primary structure of 5.8 S rRNA from the crustacean Artemia salina. The preparation shows length heterogeneity at the 5'-terminus, but consists of uninterrupted RNA chains, in contrast to some insect 5.8 S rRNAs, which consist of two chains of unequal length separated in the gene by a short spacer.
Antoon Vandenberghe   +2 more
openaire   +3 more sources

Polysomally Protected Viruses [PDF]

open access: yesPhys. Biol. 18 046009 (2021), 2021
It is conceivable that an RNA virus could use a polysome, that is, a string of ribosomes covering the RNA strand, to protect the genetic material from degradation inside a host cell. This paper discusses how such a virus might operate, and how its presence might be detected by ribosome profiling.
arxiv   +1 more source

Growth-laws and invariants from ribosome biogenesis in lower Eukarya [PDF]

open access: yesPhys. Rev. Research 3, 013020 (2021), 2020
Eukarya and Bacteria are the most evolutionarily distant domains of life, which is reflected by differences in their cellular structure and physiology. For example, Eukarya feature membrane-bound organelles such as nuclei and mitochondria, whereas Bacteria have none.
arxiv   +1 more source

An improved direct RNA sequence method; its application to Vida faba 5.8S ribosomal RNA

open access: greenNucleic Acids Research, 1980
We have developed a direct read-off sequencing procedure, based on the method of Stanley and Vassilenko using E. coli 5S ribosomal RNA as a model compound. Radioactive bands were transferred from an acrylamide gel fractionation in the first dimension onto a DEAE-cellulose thin layer plate. After in situ enzymatic digestion with RNase T2, mononucleoside
Yuya Tanaka   +2 more
openalex   +5 more sources

USE OF SEQUENCING METHODS FOR SPECIES IDENTIFICATION EXEMPLIFIED BY PHYLOGENETIC RELATIONSHIPS WITHIN GENUS HEDYSARUM L.

open access: yesФармация и фармакология (Пятигорск), 2021
At the moment, a relevant objective in pharmacognosy, is the use of all kinds of the DNA analysis methods for identifying plant materials, detecting counterfeits, genetically modified crops and products.The aim of the research is to study the possibility
D. R. Imachueva   +3 more
doaj   +1 more source

Traffic of interacting ribosomes: effects of single-machine mechano-chemistry on protein synthesis [PDF]

open access: yesPhysical Review E 75, 021902 (2007), 2006
Many ribosomes simultaneously move on the same messenger RNA (mRNA), each separately synthesizing the protein coded by the mRNA. Earlier models of ribosome traffic represent each ribosome by a ``self-propelled particle'' and capture the dynamics by an extension of the totally asymmetric simple exclusion process (TASEP).
arxiv   +2 more sources

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