By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang +27 more
wiley +1 more source
Heterogeneity in gender differences in self-reported political preferences, trust, and well-being across 39 European countries. [PDF]
Yang Y +4 more
europepmc +1 more source
Gender Equality in Islamic Education: Promoting Democratic Values and Advancing SDGs 4 & 5
Muhammad Ikhlasul Amal +2 more
openalex +2 more sources
Cancer‐Like Fragmentomic Characteristics of Somatic Variants in Cell‐Free DNA
We report that in non‐cancerous subjects, cell‐free (cfDNA) molecules harboring somatic variants exhibit cancer‐like fragmentomic characteristics associated with clonal hematopoiesis. Importantly, these somatic variant‐associated fragmentomic aberrations are more pronounced in cancer patients. Leveraging such somatic variant‐associated signals in cfDNA,
Zhenyu Zhang +12 more
wiley +1 more source
The role of teachers' language usage in the relationship between their awareness toward the concept of gender equality and gender pedagogy practice in upper primary schools. [PDF]
Berhanu KZ, Ayele WG, Naidoo P.
europepmc +1 more source
Meta‐GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility
This study incorporated 14 210 individuals to perform a GWAS meta‐analysis of six semen quality traits. The GWAS meta‐analysis identifies 234 GWAS loci associated with semen quality traits. The incorporation with a functional genomics resource explains potential genetic regulation of ∼40% GWAS signals underlying semen quality traits.
Qing Lin +26 more
wiley +1 more source
Gender and income disparities in World Psychiatry Congress participation (2023-2024). [PDF]
Yilmaz-Karaman IG +5 more
europepmc +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
Children and Young Adults Factor Merit Into Their Judgments of Gender-Based Science Resource Inequalities. [PDF]
Forbes MB, Sims RN, Killen M.
europepmc +1 more source

