Results 91 to 100 of about 9,918,450 (306)
Ifigênia e o Campo de Visão: poesia visionária
Pitágoras 500, 2013 O presente artigo analisa a peça Ifigênia, da Cia. Elevador de Teatro Panorâmico. O espetáculo tem dramaturgia de Cássio Pires, a partir de Ifigênia em Áulis, de Eurípides.
Michelle Gonçalves, Marcelo Lazzaratto
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Crime and Punishment in the "American Dream" [PDF]
We observe that countries where belief in the "American dream" (i.e., effort pays) prevails also set harsher punishment for criminals. We know from previous work that beliefs are also correlated with several features of the economic system (taxation ...
Di Tella, Rafael, Dubra, Juan
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, 2016 We present the stellar mass-halo mass scaling relation for 46 X-ray selected low-mass clusters or groups detected in the XMM-BCS survey with masses $2\times10^{13}M_{\odot}\lesssim M_{500}\lesssim2.5\times10^{14}M_{\odot}$ at redshift $0.1\le z \le1.02$.
Bocquet, S. +8 more
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Pitágoras 500, 2013 É com imenso prazer que lançamos o quarto volume da Pitágoras 500, periódico que tem se dedicado a publicar artigos sobre a arte teatral. Neste número, contamos com a colaboração de autores que discutem a condição do trágico e da(s) tragédia(s ...
Elen de Medeiros
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A New Stock Index to Better Predict the United States\u27 Real GDP [PDF]
, 2010 The relationship between the United States’ real GDP and the overall stock market has been acknowledged by researchers and investors alike. This research paper will document a newly created composite index that will try to more accurately predict the ...
Nette, William
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Bob Wilson e sua relação biográfica com as deficiências
Pitágoras 500, 2018 O presente artigo busca sublinhar a relação artístico-biográfica do encenador norte-americano Bob Wilson com as deficiências. Os eventosaqui destacados ocorreram antes de sua investida profissional nas artes da cena, porém são de fundamental importância ...
Lucas Pinheiro
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Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source