Results 191 to 200 of about 1,823,440 (329)

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

European Food Law, red. L. Costato, F. Albissini, Wolters Kluwer Italia, Seggiano di Pioltello 2012, ss. 510.

, 2012
Kamila Błażejewska, Roman Budzinowski
openalex   +1 more source

The Development Philosophy for Rolling Stocks Originated from Series 510 (1931) in Tokyu Corporation

, 2015
Toshio Ogihara
openalex   +1 more source

Mammalian Proteome Profiling Reveals Readers and Antireaders of Strand‐Symmetric and ‐Asymmetric 5‐Hydroxymethylcytosine‐Modifications in DNA

Advanced Science, EarlyView.
We investigate by proteomics studies how strand‐symmetric and ‐asymmetric cytosine 5‐modifications in DNA are selectively recognized by the nuclear proteome. Using promoter probes with defined modification patterns, we identify tissue‐specific reader proteinsincluding MYC, MAX, and RFX5that discriminate 5‐hydroxymethylcytosine symmetry and sequence ...
Lena Engelhard, Zeyneb Vildan Cakil, Marlon S. Zambrano‐Mila, Simone Eppmann, Tye Gonzalez, Rasmus Linser, Petra Janning, Sidney Becker, Daniel Summerer   +8 more
wiley   +1 more source

Development of a robust corpus for automated evaluation of online health information in Chinese using the DISCERN scale. [PDF]

J Am Med Inform Assoc
E T, Li X, Liang J, Ma J, Fang Q, Chen S, Lei J, Chute CG.   +7 more
europepmc   +1 more source

Electrochemiluminescence Drives Photodynamic Therapy In Vivo

Advanced Science, EarlyView.
Electrochemiluminescence (ECL)‐driven photodynamic therapy (PDT) for in vivo cancer treatment is reported for the first time. The flexible ECL patch exhibits stable and intense luminance under alternating current voltage, enabling efficient photosensitization to generate reactive oxygen species that damage cancer cells, thus leading to significant ...
Jia‐Bao Lin, Ling‐Ling Xu, Yong Liu, Hang Gao, Hong‐Yuan Chen, Jing‐Juan Xu   +5 more
wiley   +1 more source

Molecular epidemiology and antimicrobial susceptibility of group A Streptococcus isolated from children in Greece during 2023. [PDF]

Infection
Tatsi EB, Dellis C, Dourdouna MM, Rizou A, Paradeisis G, Koutouzi FI, Georgakopoulou T, Stathi A, Doudoulakakis A, Kalogeras G, Zachariadou L, Kontopoulou K, Michos A.   +12 more
europepmc   +1 more source

MicroRNA-510-3p and Its Gene Network in the Disease Regulation of Preeclampsia: An Insilico Approach

, 2023
Sushmaa Chandralekha Selvakumar, K Auxzilia Preethi, Kehinde Ross, Deusdedit Tusubira, Durairaj Sekar   +4 more
openalex   +1 more source

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Use of Psychoactive Substances Before Incarceration Among Prison Inmates With Drug Abuse or Dependence: Data From the OPPIDUM Program. [PDF]

Fundam Clin Pharmacol
Abbas Z, Lacroix C, Jouve E, Eiden C, Micallef J, Peyrière H, and the French Addictovigilance network.   +6 more
europepmc   +1 more source